Results 151 to 160 of about 6,051 (258)

Spinal Implant–Associated Infection in Type 2 and Type 1 Diabetes: Phenotype‐Specific Inflammatory Features and Therapeutic Response to Semaglutide

JOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Diabetes mellitus (DM) is a major risk factor for postoperative infection and wound complications in spine surgery, yet distinctions between Type 2 (T2DM) and Type 1 (T1DM) pathophysiology are rarely addressed. This study compares infectious burden, wound healing, and immune response among a murine model of spinal implant‐associated
Thomas E. Olson, Trevor S. Lloyd, Christopher D. Hamad, Rene F. Chun, Joshua Wiener, Autreen Golzar, Joshua Mehany, Soroush Shahamatdar, Andrew Kittredge, Lauren Pearce, Kevin P. Francis, Farres Obeidin, Langston T. Holly, Michael R. Yeaman, John S. Adams, Nicholas M. Bernthal, William L. Sheppard   +16 more
wiley   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Peak Inspiratory Flow Capability for Simulated Dry Powder Inhaler Resistances in Asthma Patients Prescribed Pressurized Metered-Dose Inhalers with Valved Holding Chambers: The USE-DPI Study. [PDF]

J Clin Med
Bravo Quiroga L, González Moro JM, Álvarez-Gutiérrez FJ, Baynova K, De La Poza Abad M, Izquierdo Alonso JL.   +5 more
europepmc   +1 more source

Detection and Characterization of ESBL‐Producing and Carbapenem‐Resistant Klebsiella pneumoniae in Ornamental Birds and Their Surrounding Environments

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multidrug‐resistant ESBL‐ and carbapenem‐resistant Klebsiella pneumoniae were identified from ornamental birds, their handlers and surrounding environments, carrying key virulence and resistant genes, highlighting potential One Health transmission risks between animals, humans and the associated environments.
Md Abdullah Evna Hasan, Md. Liton Rana, Md Saiful Islam, Sadia Afrin Punom, Md. Tabeer Hossain Antor, Diruba Akter Jany, Naeem Ahammed Ibrahim Fahim, S M Abu Sama Al Faruquee, Md. Raisul Islam, Zuhayr Bakhtiyar, Anindita Ash Prome, Md. Monirul Islam, Saifur Rahman, Mohammad Ferdousur Rahman Khan, Md. Tanvir Rahman   +14 more
wiley   +1 more source

Utilization and access to metered-dose inhalers and sustainable alternatives among older adults in the United States: a population-based study. [PDF]

Lancet Reg Health Am
Parthasarathi A, Iwata I, Chen C, Li AR, Lye N, Gandhi P, Rua M, Panettieri RA, Radbel J, Anand MP, Bridgeman M, Setoguchi S.   +11 more
europepmc   +1 more source

Need for Developing a Collapsible and Inexpensive Spacer Device for Use with Metered Dose Inhalers

, 2001
Most of the patients with asthma or COPD (Chronic Obstructive Pulmonary Disease) in the United States require the use of metered dose inhalers (MDIs) to control their symptoms.
Bercich, Brian L.
core  

Preclinical Quantitative In Vivo MRI Assessment of Exogenous Surfactant Pulmonary Distribution After Clinically Relevant Intratracheal Delivery

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Quantitative in vivo contrast‐enhanced UTE MRI enables sensitive and precise mapping of pulmonary surfactant distribution, revealing peripheral localization and homogeneous distal penetration under physiological conditions. Comparison with ex vivo models highlights the role of physiological processes in surfactant retention.
Oumaima Marfouk, Rémy Gérard, Ghalia Kaouane, Lara Leclerc, Noël Pinaud, Michael Fayon, Sophie Périnel‐Ragey, Jérémie Pourchez, Eric Dumas De La Roque, Yannick Crémillieux   +9 more
wiley   +1 more source

Impact of Video-Assisted Teaching on Knowledge and Practice Regarding the Use of Metered Dose Inhalers Among Patients With Obstructive Respiratory Disorders. [PDF]

Cureus
Karadkar GU, Choudhary RP.
europepmc   +1 more source

Subcutaneous terbutaline as an alternative to metered-dose inhalers for asthma during the COVID-19 pandemic. [PDF]

J Am Coll Emerg Physicians Open, 2020
Strauss RA.
europepmc   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source