Results 41 to 50 of about 6,051 (258)

Evaluation of asthma control, parents’ quality of life and preference between AeroChamber Plus and AeroChamber Plus Flow-Vu spacers in young children with asthma

, 2015
Objective: The AeroChamber Plus (AC) valved holding chamber has been enhanced to include the Flow-Vu (FV) inspiratory flow indicator that provides visual inhalation feedback during use. We have investigated if FV alters asthma control and whether parents
Toor, Sophie, Ammari, Wesam G., Stephenson, John, Chrystyn, Henry, Chetcuti, Philip   +4 more
core   +1 more source

The Inhalation Characteristics of Patients When They Use Different Dry Powder Inhalers

, 2015
Background: The characteristics of each inhalation maneuver when patients use dry powder inhalers (DPIs) are important, because they control the quality of the emitted dose.
Stephenson, John, Chrystyn, Henry, Azouz, Wahida, Saralaya, Dinesh, Chetcuti, Philip, Hosker, Harold S.R., Hosker, Harold S R   +6 more
core   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control

, 2009
Background As more inhaled corticosteroid (ICS) devices become available, there may be pressure for health-care providers to switch patients with asthma to cheaper inhaler devices. Our objective was to evaluate impact on asthma control of inhaler device
Williams, Angela E., Chrystyn, Henry, von Ziegenweidt Julie, Andrew Lloyd, Thomas, Mike, Mike Thomas, Henry Chrystyn, Angela E Williams, Lloyd, Andrew, Chrystyn Henry, von Ziegenweidt, Julie, Price David, Price, David, Julie von Ziegenweidt, Thomas Mike, Lloyd Andrew, Williams Angela E, David Price   +17 more
core   +1 more source

Hair analysis of formoterol as a novel tool to assess long‐term inhalation medication adherence: Data from the TRICOLON trial

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this paper is to examine inhaled formoterol concentrations in hair and assess the potential of hair analysis as a tool for measuring long‐term adherence, by validation with objective data from digital inhalers. Methods Hair samples and digital inhaler data were collected from patients with COPD in 10 hospitals in the Netherlands as part ...
Liz J. A. Cuperus, A. Mireille A. Wessels, Huib A. M. Kerstjens, Daan J. Touw, Erik W. M. A. Bischoff, Job van der Palen, Arnoud Aldenkamp, Astrid van Huisstede, Folkert Brijker, Stephan Dik, Lidwien Graat‐Verboom, Martijn Goosens, Peter Th. W. van Hal, Jolanda C. Kuijvenhoven, Lisette I. Z. Kunz, Renske van der Meer, Mariette H. A. Scholma‐Bronsema, Job F. M. van Boven, Johannes C. C. M. in't Veen, the TRICOLON study group, Marjo van der Poel, Irini Piso, Marijke Amelink, Anke Rol, Jennifer de Graaf, Petra Hirmann, Fleur van Tour, Elly Jordens, Lydia Alfing, Gerda Lenderink, Truus Rietveld, Jasmijn van Campen, Jantine de Bruijn, Janice van ter Burg, Liselore Baarssmit, Walter van Litsenburg, Len Knoops, Margot Eggermont‐Schilt, Manon de Waard‐Heijligers, Ilonka Paalvast‐Schouten, Mariette Scholma, Sandra Brookman‐Mozes, Inge Paas, Lidwien Verboom, Karin van Mierlo‐Snoeijs   +44 more
wiley   +1 more source

A study of factors affecting nucleation and bubble growth in pressurised metered dose inhalers [Abstract] [PDF]

, 2017
A study of factors affecting nucleation and bubble growth in pressurised metered dose inhalers ...
Graham Hargrave (1258908), Gary Smith (232827), Hendrik Versteeg (1248945), N. Nezami (7209242)   +3 more
core   +1 more source

Liquid resistivity of pharmaceutical propellants using novel resistivity cell

Scientific Reports, 2023
Metered-dose inhalers employ propellants to produce pharmaceutical aerosols for treating respiratory conditions like asthma. In the liquid phase, the DC volume resistivity of pharmaceutical propellants, including R134a, R152a, and R227ea, was studied at ...
Hussein Ahmad, Manoochehr Rasekh, Nadarajah Manivannan, Wamadeva Balachandran   +3 more
doaj   +1 more source

Goal Displacement and Goal Conflicts in Circular Innovation Initiatives: Types and Mitigation Practices

Business Strategy and the Environment, EarlyView.
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim, Johan Frishammar, Debadrita Panda   +2 more
wiley   +1 more source

Estimation of Particle Deposition in the Airways from Different Inhaler Formulations Using an In Silico Model

KONA Powder and Particle Journal, 2014
The objective of these studies was to evaluate the use of an in silico model for predicting lung deposition of inhaled therapeutic aerosols.
Hugh D.C. Smyth, Ted B. Martonen, Kristin K. Isaacs, Anthony J. Hickey   +3 more
doaj   +1 more source

Comparison of Salbutamol Delivered Via Jet Nebulizer With A Metered Dose Inhaler (MDI) Plus A Spacer for Asthma Exacerbation of Children: A Randomized Clinical Trial

Acta Medica Iranica, 2020
Asthma is the most common chronic illness in children and is a major reason for pediatric emergency department visits. Beta-2 agonists are considered the most effective drugs for immediate relief in the symptoms.
Seyyed Ahmad Tabatabaii, Mahdieh Vahedi, Ghamartaj Khanbabaee, Saeed Sadr, Nazanin Farahbakhsh   +4 more
doaj   +1 more source