Results 61 to 70 of about 6,051 (258)

Human Health Risk Assessment From Exposure to Toxic Metals in Soils and Leafy Vegetables in Smallholder Farms of Northeastern Brazil

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study assessed human health risks associated with exposure to potentially toxic metals (PTMs) in soils and leafy vegetables cultivated in smallholder agricultural systems in Northeastern Brazil. Soil and vegetable samples were collected from 18 agricultural areas and analyzed for cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe), nickel
Fernando Ferreira da Cunha Filho, Alex Souza Moraes, João Paulo Siqueira da Silva, Edvane Borges da Silva, Ademir Amaral, André Maciel Netto   +5 more
wiley   +1 more source

Optimizing the Delivery of Inhaled Medication for Respiratory Patients: The Role of Valved Holding Chambers

Canadian Respiratory Journal, 2018
Valved holding chambers (VHCs) have been used with pressurized metered-dose inhalers since the early 1980s. They have been shown to increase fine particle delivery to the lungs, decrease oropharyngeal deposition, and reduce side effects such as throat ...
R. Andrew McIvor, Hollie M. Devlin, Alan Kaplan   +2 more
doaj   +1 more source

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

Life cycle environmental impacts of inhalers [PDF]

, 2019
Pressurised metered-dose inhalers are a method of choice for delivering drugs into lungs for the treatment of asthma and chronic obstructive pulmonary disease across the globe.
Jeswani, Harish Kumar, Azapagic, A.; id_orcid   +1 more
core   +1 more source

Longitudinal 1H and 129Xe Lung MRI in Patients With Post‐COVID Residual Lung Abnormalities

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background It is unclear how lung function may recover in patients with residual lung abnormalities (RLAs) following COVID‐19 pneumonia. Purpose To evaluate lung function trends over time in patients with RLAs following hospitalization due to COVID‐19. Study Type Prospective, multicenter longitudinal cohort study.
Laura C. Saunders, Guilhem J. Collier, Laurie J. Smith, Ho‐Fung Chan, Paul J. C. Hughes, Scarlett Strickland, Lotta Gustafsson, Thomas Newman, Megan Plowright, Zoë Gabriel, Lily M. Pearce, James T. Grist, Kher Lik Ng, Arthur Harrison, Charlotte E. Bolton, Jody Bray, Helen Marshall, Graham Norquay, Alberto M. Biancardi, Jimmy E. Ball, Neil J. Stewart, Kevin M. Johnson, Andrew J. Swift, Smitha Rajaram, John Blaikley, Stefan Stanel, Paul J. Collini, Gary H. Mills, Rod Lawson, Jonathan Brooke, Amanda T. Goodwin, Iain D. Stewart, Ling‐Pei Ho, Joseph Jacob, Thomas Meersmann, Galina E. Pavlovskaya, Fergus Gleeson, Ian P. Hall, Gisli Jenkins, Jim M. Wild, A. A. Roger Thompson, on behalf of the UK‐ILD consortium   +41 more
wiley   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Dispersion and Characterization of Pharmaceutical Dry Powder Aerosols

KONA Powder and Particle Journal, 2014
Dry powder inhalers may be employed for the delivery of drugs to the lungs for the treatment of pulmonary and systemic diseases. Dry powder inhalers consist of a formulation, metering system and delivery device.
Craig A. Dunber, Anthony J. Hickey, Peter Holzner   +2 more
doaj   +1 more source

Paraben Exposure in the General Taiwanese Population: Reference Values, Personal Care Products, and Cumulative Risk Assessment

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Parabens (parahydroxybenzoates), which are frequently used as preservatives in pharmaceuticals, foodstuffs, and personal care products, have recently attracted considerable attention due to their adverse health effects and endocrine‐disrupting properties.
Jung‐Wei Chang, Yen‐Hsuan Huang, Hsin‐Chang Chen, Vinoth Kumar Ponnusamy, Wan‐Ting Chang, Po‐Chin Huang   +5 more
wiley   +1 more source

Avaliação do conhecimento sobre o uso de inaladores dosimetrados entre profissionais de saúde de um hospital pediátrico Evaluation of the knowledge of health professionals at a pediatric hospital regarding the use of metered-dose inhalers

Jornal Brasileiro de Pneumologia, 2008
OBJETIVO: Avaliar os conhecimentos sobre o uso e manejo de inaladores pressurizados dosimetrados entre profissionais de um hospital pediátrico terciário.
Fábio Pereira Muchão, Sílvia La Regina Rodrigues Perín, Joaquim Carlos Rodrigues, Cláudio Leone, Luiz Vicente Ribeiro Ferreira Silva Filho   +4 more
doaj   +1 more source