Results 211 to 220 of about 302,269 (383)

GDF15 mediates the effects of metformin on body weight and energy balance

Nature, 2019
A. Coll, Michael Chen, Pranali Taskar, D. Rimmington, Satish Patel, J. Tadross, I. Cimino, Ming Yang, P. Welsh, S. Virtue, Deborah A. Goldspink, Emily L. Miedzybrodzka, A. Konopka, Raul Ruiz Esponda, Jeffrey T.-J. Huang, Y. C. Tung, S. Rodriguez-Cuenca, R. Tomaz, H. Harding, A. Melvin, Giles S. H Yeo, D. Preiss, A. Vidal-Puig, L. Vallier, K. S. Nair, N. Wareham, D. Ron, F. Gribble, F. Reimann, N. Sattar, David B. Savage, Bernard B Allan, S. O’Rahilly   +32 more
semanticscholar   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Pregnancy and its Outcomes in Polycystic Women Treated with Metformin and Ovulation Induction Medicines

Journal of Rawalpindi Medical College, 2014
Background: To study the effectiveness of Metformin in attaining pregnancy along with ovulation induction medicines in infertile women with polycystic ovary syndrome (PCOS) and to determine beneficial effect of Metformin when taken during pregnancy ...
Asma Irfan
doaj  

Role of Metformin Monotherapy Vs Metformin Plus Dapagliflozin in New Onset T2DM Among 40 Plus Obese Women in Glycaemic Control

JK Science
Objective: A Randomized, open-label comparative clinical study was conducted to evaluate the comparative efficacy and safety of Metformin 500mg twice daily versus Metformin 500mg twice daily Plus Dapagliflozin (10mg) once daily in achieving glycemic ...
Amarjeet Singh, Ashima Badyal, Suman Kotwal, Vishal R Tandon   +3 more
doaj  

Overcoming the barriers to effective glycaemic control for type 2 diabetes [PDF]

, 2002
American Association of Clinical Endocrinologists., American Diabetes Association, Bailey CJ, Banerji MA, Banerji MA, Blonde L., Burkhard Göke, Charles A Reasner, Guidelines Subcommittee., Haupt E., Liebl A., Morris AD   +11 more
core   +1 more source

Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. [PDF]

, 2000
Edward S. Horton, Cynthia Clinkingbeard, Marjorie Gatlin, James E. Foley, S. Mallows, Steven S. Shen   +5 more
openalex   +1 more source

Angiotensin receptor‐neprilysin inhibitors in concurrent heart failure with reduced ejection fraction and kidney failure

ESC Heart Failure, EarlyView.
Abstract Aims Angiotensin receptor‐neprilysin inhibitor (ARNI) therapy has demonstrated improved outcomes in heart failure with reduced ejection fraction (HFrEF). However, its benefits in patients with concomitant kidney failure undergoing replacement therapy remain uncertain. Methods and results Using the National Health Insurance Service database, we
Mi‐Hyang Jung, Dong‐Hyuk Cho, Jimi Choi, Mi‐Na Kim, Chan Joo Lee, Jung‐Woo Son, Yaeni Kim, Jong‐Chan Youn, Byung‐Su Yoo   +8 more
wiley   +1 more source

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

Nature Network Boston, 2018
Lulu Sun, Cen Xie, Guang Wang, Yuehua Wu, Qing Wu, Xuemei Wang, Jia Liu, Yangyang Deng, Jialin Xia, Bo Chen, Songyang Zhang, Chuyu Yun, Guan Lian, Xiujuan Zhang, Heng Zhang, William H. Bisson, Jingmin Shi, XiaoXia Gao, Pupu Ge, Cuihua Liu, K. Krausz, Robert G. Nichols, Jingwei Cai, Bipin Rimal, A. Patterson, Xian Wang, F. Gonzalez, Changtao Jiang   +27 more
semanticscholar   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso, Davide Stolfo, Markus S. Anker, Antoni Bayes‐Genis, Ovidiu Chioncel, Stephane Heymans, Pardeep S. Jhund, Basil S. Lewis, Gary D. Lopaschuk, Lars H. Lund, Arantxa Gonzalez, Matteo Pagnesi, Gabriele Giacomo Schiattarella, Carlo Gabriele Tocchetti, Peter van der Meer, Sophie Van Linthout, Sven Wassmann, B. Daan Westenbrink, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese   +20 more
wiley   +1 more source