Results 301 to 310 of about 320,201 (374)

Circulating Profiles of the Bile Acid Metabolomics in Patients With Polycystic Ovary Syndrome Treated With Metformin or Canagliflozin. [PDF]

Pharmacotherapy
Yan Q, Cai M, Wang N, Wu W, Zhang H, Zhu Y, Luo J, Zhang M, Li J.   +8 more
europepmc   +1 more source

In‐Tumor CRISPR‐Cas9 Knockout Screening and Novel Therapy Development for Malignant Transformation of Ovarian Teratoma

Cancer Science, EarlyView.
We conducted an in vivo genome‐wide CRISPR‐Cas9 knockout screen using MTMCT‐derived cells to identify genes essential for tumor growth. SOD1 emerged as a key therapeutic target, and its inhibition suppressed tumor proliferation by disrupting redox homeostasis, both in vitro and in PDX models. ABSTRACT Malignant transformation of mature cystic teratoma (
Satoshi Tamauchi, Kosuke Yoshida, Wang Xinyuan, Atsushi Nakagawa, Akira Yokoi, Nobuhisa Yoshikawa, Kaoru Niimi, Yusuke Yamamoto, Hiroaki Kajiyama   +8 more
wiley   +1 more source

Efficacy of immediate-release versus extended-release metformin on glycemic control and insulin resistance in Saudi patients with type 2 diabetes: A prospective cohort study. [PDF]

J Taibah Univ Med Sci
Alshadfan HS, Mirghani HO, Alrasheed TK, Abdullah MNH.   +3 more
europepmc   +1 more source

Cognitive Impairment in Diabetes - The Causality Association with Metformin

, 2019
Yeshwanth Hutchaiah, Archith Boloor, Alister Thomas   +2 more
openalex   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Retraction: Potassium bromate-induced nephrotoxicity and potential curative role of metformin loaded on gold nanoparticles. [PDF]

Sci Prog
europepmc   +1 more source

Cerebrovascular Function in Women With Polycystic Ovary Syndrome: A Pilot Multi‐Parameter Magnetic Resonance Imaging Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is associated with an increased risk of cerebrovascular disease, but the effects on cerebrovascular function are unknown. In this pilot study, we sought to compare cerebrovascular perfusion, pulsatility, reactivity and metabolism between women with PCOS and healthy volunteers using MRI, and ...
Melissa E. Wright, Cory T. Richards, Saajan Davies, Rachel N. Lord, D. Aled Rees, Kevin Murphy   +5 more
wiley   +1 more source

Impact of metformin on intervertebral disc degeneration in patients with diabetes: a prospective cohort study from the UK biobank. [PDF]

Diabetol Metab Syndr
Chen J, Liao N, Gao B, Liang T, Hu W, Zhang Z, Choi W, Shi H, Liu S, Chen Y, Lin Y, Deng Z, Qiu X, Huang D, Gao W.   +14 more
europepmc   +1 more source