Results 361 to 370 of about 303,514 (383)
Some of the next articles are maybe not open access.
Scandinavian Journal of Haematology, 1969
A clinical series of 40 patients was observed for 5 months, in the course of which every patient took 1.5 g. metformin daily for 3 months. No increase in fibrinolytic activity was demonstrable by euglobulin lysis test during the course of treatment. Nor did the fibrinogen and cholesterol values change. Blood glucose decreased.
openaire +3 more sources
A clinical series of 40 patients was observed for 5 months, in the course of which every patient took 1.5 g. metformin daily for 3 months. No increase in fibrinolytic activity was demonstrable by euglobulin lysis test during the course of treatment. Nor did the fibrinogen and cholesterol values change. Blood glucose decreased.
openaire +3 more sources
Diabetes & Metabolism, 2014
These case reports demonstrate that, at the individual level, blood metformin concentrations and metformin effects on lactate do not always correlate.We report here on two unusual cases: metformin accumulation in the absence of hyperlactataemia; and metformin-induced hyperlactataemia with no metformin accumulation.Patient #1 presented with severe ...
Rachel Desailloud +4 more
openaire +3 more sources
These case reports demonstrate that, at the individual level, blood metformin concentrations and metformin effects on lactate do not always correlate.We report here on two unusual cases: metformin accumulation in the absence of hyperlactataemia; and metformin-induced hyperlactataemia with no metformin accumulation.Patient #1 presented with severe ...
Rachel Desailloud +4 more
openaire +3 more sources
Drugs, 2005
The thiazolidinedione rosiglitazone and the biguanide metformin are effective antihyperglycaemic agents with different modes of action; rosiglitazone primarily increases insulin sensitivity, whereas metformin primarily reduces hepatic glucose output. Antihyperglycaemic combination therapy is often required to achieve effective glycaemic control.
openaire +3 more sources
The thiazolidinedione rosiglitazone and the biguanide metformin are effective antihyperglycaemic agents with different modes of action; rosiglitazone primarily increases insulin sensitivity, whereas metformin primarily reduces hepatic glucose output. Antihyperglycaemic combination therapy is often required to achieve effective glycaemic control.
openaire +3 more sources
2016
Metformin is the most widely prescribed antidiabetic drug in the world. Despite its beneficial effects in reducing the risk for developing vascular complications associated with diabetes, the glycemic response to metformin is highly variable. Genetic factors, along with factors such as various comorbidities and body weight, contribute to this ...
Yee, Sook Wah +2 more
openaire +3 more sources
Metformin is the most widely prescribed antidiabetic drug in the world. Despite its beneficial effects in reducing the risk for developing vascular complications associated with diabetes, the glycemic response to metformin is highly variable. Genetic factors, along with factors such as various comorbidities and body weight, contribute to this ...
Yee, Sook Wah +2 more
openaire +3 more sources
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2016
Metformin is the first choice among drugs used for the treatment of type II diabetes mellitus mainly because of several advantages: proven hypoglycemic effect, good safety profile, virtually no risk of hypoglycemia, body weight reduction, lipid-lowering effect, efficacy in preventing micro- and macrovascular complications as well as adverse cardiac and
Sessa C +5 more
openaire +2 more sources
Metformin is the first choice among drugs used for the treatment of type II diabetes mellitus mainly because of several advantages: proven hypoglycemic effect, good safety profile, virtually no risk of hypoglycemia, body weight reduction, lipid-lowering effect, efficacy in preventing micro- and macrovascular complications as well as adverse cardiac and
Sessa C +5 more
openaire +2 more sources