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Controlled Release of Metformin Hydrochloride from Core-Shell Nanofibers with Fish Sarcoplasmic Protein. [PDF]
Sena S +13 more
europepmc +1 more source
Hydrogel-forming microneedles enhance transdermal delivery of metformin hydrochloride. [PDF]
Migdadi EM +7 more
europepmc +1 more source
Transdermal metformin hydrochloride-loaded cubic phases: in silico formulation optimization, preparation, properties, and application for local treatment of melanoma. [PDF]
Yu X, Zhou W, Wang H, Lu S, Jin Y, Fu J.
europepmc +1 more source
Innovative Biosensor Platforms for the Detection of Metformin in Diabetes Management. [PDF]
Jafarzadeh S +6 more
europepmc +1 more source
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Metformin hydrochloride: An antihyperglycemic agent
American Journal of Health-System Pharmacy, 1997The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, drug interactions, and dosage and administration of metformin hydrochloride are reviewed. Metformin is an antihyperglycemic agent; it lowers the blood glucose concentration without causing hypoglycemia.
Michael W Kelly
exaly +3 more sources
Structure of metformin hydrochloride
Acta Crystallographica Section C Crystal Structure Communications, 1989N,N-Dimethylbiguanide hydrochloride, C 4 H 12 N 5 .Cl, M r =165.6, monoclinic, P2 1 /a, a=7.991(3), b=13.950(5), c=8.020(2)A, β=114.98(3)°, V=810.4(5)A 3 , Z=4, D m =1.35(1), D x =1.357Mgm -3 , MoKα, λ=0.7107A, μ=0.41mm -1 , T=295K, F(000)=352.0, R=0.038 and wR=0.032 for 980 observed reflections with I>3σ(I).
M. Hariharan, S. S. Rajan, R. Srinivasan
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Development of novel mucoadhesive pellets of metformin hydrochloride
Archives of Pharmacal Research, 2009Mucoadhesive polymer-coated pellets containing metformin hydrochloride were prepared by the powder-layering technique using a centrifugal fluidizing (CF)-granulator. Four high-viscosity polymers were applied to make the pellets: 1) hydroxymethylcellulose (HPMC), 2) sodium alginate (Na-Alg), 3) HPMC/Carbopol, and 4) sodium carboxylmethylcellulose (Na ...
Jingshu, Piao +8 more
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Extended-Release Metformin Hydrochloride
Treatments in Endocrinology, 2004In the new oral, once-daily, extended-release (ER), single-composition osmotic tablet formulation of the biguanide metformin hydrochloride (metformin XT), metformin is released at a controlled rate from a central osmotic tablet core through a semipermeable coating.
Antona J, Wagstaff, David P, Figgitt
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