Development and validation of analytical procedure for analysis of polyvinylpyrrolidone in tablets containing metformin hydrochloride and pioglitazone hydrochloride [PDF]
Polyvinylpyrrolidone (PVP) is a common excipient in pharmaceutical formulations due to its inert, biocompatible, and multifunctional properties. However, its presence can impact drug release.
Sri Paryanti +2 more
doaj +3 more sources
Hypoglycemic, hypolippidemic and antioxidant effects of leaves methanolic extract of Baccaurea ramiflora [PDF]
The present study was designed for investigating the hypoglycemic, hypolipidemic and antioxidant activity of the leaves of B. ramiflora. Antioxidant potential was assayed by measuring the free radical scavenging activity using 1, 1-diphenyl-2 ...
Ahmed, Mohammad Towhir +5 more
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<b>Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation</b>
Metformin hydrochloride (MH) is an oral hypoglycemic agent and a high-dose drug that has poor flow and compression properties. In this study, the feasibility of developing adequate, low cost 500mg tablets of metformin hydrochloride by wet granulation was
LUCIANA CATIA BLOCK +6 more
doaj
Potential Therapeutic Drugs for Parkinson’s Disease Based on Data Mining and Bioinformatics Analysis
The objective is to search potential therapeutic drugs for Parkinson’s disease based on data mining and bioinformatics analysis and providing new ideas for research studies on “new application of conventional drugs.” Method differential gene candidates ...
Chuan Xu +4 more
doaj +1 more source
A newly developed FIA-merging zones spectrophotometric system, the method is rapid, accurate and sensitive for metformin hydrochloride determination through the oxidation of 1- naphthol by sodium hypochlorite and coupling with metformin.HCl in the ...
Bushra Basheer Qassim
doaj
Smartphone-Assisted Thin-Layer Chromatography for Rapid Quality Screening of Metformin
Type II diabetes remains a significant global public health issue, affecting both individual well-being and healthcare systems worldwide. Metformin hydrochloride is widely prescribed as the first-line treatment for managing diabetes.
Ram Kumar Bhattarai +3 more
doaj +1 more source
Improved Chromatographic Separation of Sitagliptin Phosphate and Metformin Hydrochloride
New UPLC method was developed for determination of sitagliptin and metformin using Symmetry C18 column (100 mm × 2.1 mm, 2.2 μm) and isocratic elution (methanol 20%), pH (3.5) as a mobile phase. The ultraviolet detector was operated at 220 nm and the column temperature was 50°C. Linearity parameters were acceptable over the concentration ranges of 2-12
openaire +2 more sources
Oral glucose-lowering drugs and long-term risk of benign prostatic hyperplasia
Background. One of the most prominent threats for masculine health is comorbidity between benign prostatic hyperplasia (BPH) and diabetes mellitus type 2. Many publications suppose influence of hyperglycemia on lower urinary tract obstruction.
Stanislav N. Volkov +5 more
doaj +1 more source
Cutaneous side effects of diabetes treatment [PDF]
As lesões cutâneas são frequentes na diabetes mellitus, havendo um envolvimento da pele em cerca de 30 a 91% dos doentes durante o curso da doença. Estas podem ser não infeciosas ou autoimunes, infeciosas ou resultar de complicações do tratamento da ...
Borges-Costa, J, Gomes, F
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