Comparing Hydroxypropyl Methylcellulose and Guar Gum on Sustained Release Effect of Metformin Hydrochloride Matrix Tablet [PDF]
Pharmaceutical and Biomedical ResearchBackground and Objectives: Limited diabetes drug availability and frequent adverse reactions to oral medications highlight the need for improved drug delivery. This study suggests optimizing drug efficiency through process modifications, focusing on anti-
Amlan Bishal +6 more
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Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]
, 2019 Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica +12 more
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Effect of Total Amount of Metformin HCl on the Characteristics of Metformin-Ca Alginate Microspheres
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2019 Introduction: Metformin hydrochloride (metformin HCl) is an antidiabetic drug that is specifically used for type 2 diabetes mellitus (DM) and belongs to the biguanide antidiabetic drugs.
Dewi Melani Hariyadi +2 more
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Effects of prolonged exposure to low dose metformin in thyroid cancer cell lines [PDF]
, 2017 © Ivyspring International Publisher. Background: Thyroid cancer is generally associated with an excellent prognosis, but there is significant long-term morbidity with standard treatment. Some sub-types however have a poor prognosis.
Balasubramanian, S.P. +3 more
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Plasma concentration of metformin and dexamethasone after administration through Osseogate
Drug Delivery, 2017 Background: Osseogate is a novel drug delivery route through bone marrow involving a modified implant used as the drug delivery system. The purpose of this study was to evaluate the effects of individual drug physicochemical characteristics on the ...
Hong-Kyun Kim, Young-Seok Park
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Does metformin improve vascular health in children with Type 1 diabetes? Protocol for a one year, double blind, randomised, placebo controlled trial [PDF]
, 2013 Background: Cardiovascular disease is the leading cause of mortality in Type 1 diabetes (T1D). Vascular dysfunction is an early and critical event in the development of cardiovascular disease.
Anderson, J. +7 more
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BMC ChemistryA simple, precise, and stability-indicating reverse-phase high-performance liquid chromatography method was developed and validated for the simultaneous estimation of dapagliflozin, linagliptin, and metformin hydrochloride in fixed-dose combination ...
Samkit Shah, Rajendra Kotadiya
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(Metformin-κ2N,N′)(salicylato-κ2O,O′)copper(II) trihydrate
IUCrData, 2018 The hydrous title complex [systematic name: (1,1-dimethylbiguanide-κ2N2,N4)(2-oxidobenzoato-κ2O,O′)copper(II) trihydrate], [Cu(C7H4O3)(C4H11N5)]·3H2O, was synthesized electrolytically from an ethanolic solution of metformin hydrochloride, acetylsalicylic
Sandra Julieta Gutiérrez Ojeda +3 more
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A case of fatal intoxication from metformin [PDF]
, 2015 6A case of fatal intoxication from metformin is presented. The decedent was an obese 58-year-old-woman with type II diabetes, in whom severe lactic acidosis secondary to metformin accumulation was precipitated by acute renal failure.
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New Silver Nanosensor for Nickel Traces. Part II: Urinary Nickel Determination Associated to Smoking Addiction [PDF]
, 2012 A new fluorescence silver nanosensor assisted by surfactant has been recently synthesized and applied to ultra trace nickel determination. The methodology was validated by the standard addition method and satisfactorily applied to nickel determination in
Fernandez, Liliana Patricia +2 more
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