Results 71 to 80 of about 6,618 (171)
Improved Chromatographic Separation of Sitagliptin Phosphate and Metformin Hydrochloride
International Journal of Biomedical Science, 2015 New UPLC method was developed for determination of sitagliptin and metformin using Symmetry C18 column (100 mm × 2.1 mm, 2.2 μm) and isocratic elution (methanol 20%), pH (3.5) as a mobile phase. The ultraviolet detector was operated at 220 nm and the column temperature was 50°C. Linearity parameters were acceptable over the concentration ranges of 2-12
openaire +2 more sources
Development and validation of analytical procedure for analysis of polyvinylpyrrolidone in tablets containing metformin hydrochloride and pioglitazone hydrochloride [PDF]
PharmaciaPolyvinylpyrrolidone (PVP) is a common excipient in pharmaceutical formulations due to its inert, biocompatible, and multifunctional properties. However, its presence can impact drug release.
Sri Paryanti +2 more
doaj +3 more sources
<b>Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation</b>
Revista de Ciências Farmacêuticas Básica e Aplicada, 2009 Metformin hydrochloride (MH) is an oral hypoglycemic agent and a high-dose drug that has poor flow and compression properties. In this study, the feasibility of developing adequate, low cost 500mg tablets of metformin hydrochloride by wet granulation was
LUCIANA CATIA BLOCK +6 more
doaj
Smartphone-Assisted Thin-Layer Chromatography for Rapid Quality Screening of Metformin
Advances in Pharmacological and Pharmaceutical SciencesType II diabetes remains a significant global public health issue, affecting both individual well-being and healthcare systems worldwide. Metformin hydrochloride is widely prescribed as the first-line treatment for managing diabetes.
Ram Kumar Bhattarai +3 more
doaj +1 more source
Potential Therapeutic Drugs for Parkinson’s Disease Based on Data Mining and Bioinformatics Analysis
Parkinson's Disease, 2018 The objective is to search potential therapeutic drugs for Parkinson’s disease based on data mining and bioinformatics analysis and providing new ideas for research studies on “new application of conventional drugs.” Method differential gene candidates ...
Chuan Xu +4 more
doaj +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 A newly developed FIA-merging zones spectrophotometric system, the method is rapid, accurate and sensitive for metformin hydrochloride determination through the oxidation of 1- naphthol by sodium hypochlorite and coupling with metformin.HCl in the ...
Bushra Basheer Qassim
doaj
Comparative Study of Metformin Hydrochloride Tablets in Argentina
Dissolution TechnologiesMetformin, a class III drug in the Biopharmaceutics Classification System, is an orally administered drug used to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus. Different quality parameters were assayed for Metformin immediate-release tablets (500 mg), obtained from pharmacies in Argentina, in order to ...
Brevedan, Marta Ingrid Victoria +2 more
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Oral glucose-lowering drugs and long-term risk of benign prostatic hyperplasia
Consilium MedicumBackground. One of the most prominent threats for masculine health is comorbidity between benign prostatic hyperplasia (BPH) and diabetes mellitus type 2. Many publications suppose influence of hyperglycemia on lower urinary tract obstruction.
Stanislav N. Volkov +5 more
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