Results 81 to 90 of about 6,618 (171)

Formulation and Evaluation of Metformin Hydrochloride Sublingual Film

Bangladesh Pharmaceutical Journal
Metformin hydrochloride (HCl) fast-dissolving sublingual films were formulated to enhance bioavailability and minimize side effects through rapid onset of action and optimized drug-release and dissolution characteristics. Initially, the same formulation design with different ratios of metformin HCl (Drug), polymer A and plasticizer B was used to ...
Sadia Nowshin Isla, Sreebash Chandra Bhowmik, Marzia Alam, Abdul Kuddus, Abir Hasan Pranto, Tanoy Saha, Md Saiful Islam Pathan   +6 more
openaire   +1 more source

Metformin Hydrochloride Loaded Mucoadhesive Microspheres and Nanoparticles for Anti-Hyperglycemic and Anticancer Effects Using Factorial Experimental Design. [PDF]

Drug Des Devel Ther, 2023
Kotha AA, Ahmad SU, Dewan I, Bhuiyan MA, Rahman FI, Naina Mohamed I, Reza MS.   +6 more
europepmc   +1 more source

Formulation and Evaluation of Metformin Hydrochloride Buccal Patch

International Journal of Pharmaceutical Research and Applications
Transdermal drug delivery system is a selfcontained delivery system used for topical application in the form of a multilaminated adhesive patch, which delivers a specific dose of drug at a predetermined rate and controls the drug release rate through the skin.
Rohit Kumar, Rajaram R. Rajbhar
openaire   +1 more source

Experimental Study on the Inhibition of RANKL-Induced Osteoclast Differentiation In Vitro by Metformin Hydrochloride. [PDF]

Int J Endocrinol, 2022
Chen Z, Zige L, Sai Kiang Y, Desheng C.
europepmc   +1 more source

Evaluation of Metformin Hydrochloride Tailoring Bilosomes as an Effective Transdermal Nanocarrier. [PDF]

Int J Nanomedicine, 2022
Salem HF, Nafady MM, Ali AA, Khalil NM, Elsisi AA.   +4 more
europepmc   +1 more source

Formulation And Evaluation Of Floating Microspheres Of Metformin Hydrochloride

, 2017
Metformin hydrochloride is a hypoglycemic agent used for the treatment of non-insulin dependent Diabetes mellitus. It is a BCS class III drug having high solubility and poor permeability. Plasma half life ranges from 1.5 to 3 hours and oral bioavailability is 50 to 60 %. Hence require frequent oral administration for adequate treatment of Diabetes.
openaire   +2 more sources

Metformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics. [PDF]

Sci Rep, 2021
Mady OY, Al-Shoubki AA, Donia AA, Qasim W.   +3 more
europepmc   +1 more source

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC. [PDF]

Pharmaceutics, 2022
Sha'at M, Spac AF, Stoleriu I, Bujor A, Cretan MS, Hartan M, Ochiuz L.   +6 more
europepmc   +1 more source

A Co-Doped Carbon Dot/Silver Nanoparticle Nanocomposite-Based Fluorescence Sensor for Metformin Hydrochloride Detection. [PDF]

Nanomaterials (Basel), 2022
Le TH, Kim JH, Park SJ.
europepmc   +1 more source

In vitro-in vivo availability of metformin hydrochloride-PLGA nanoparticles in diabetic rats in a periodontal disease experimental model. [PDF]

Pharm Biol, 2021
Pereira ASBF, de Souza Lima ML, da Silva-Junior AA, Dos Santos Silva E, de Araújo Júnior RF, Martins AA, Alves JSF, Oliveira AS, De Santis Ferreira L, de Araújo Costa ECT, Guerra GCB, de Medeiros CACX, Brito GAC, de Carvalho Leitao RF, de Araújo AA.   +14 more
europepmc   +1 more source