Integrating blood eosinophils and exhaled nitric oxide (FeNO) in asthma diagnostic pathways for adults and children: the PROPULSION SANTÉ observational study with translational sub-studies (DIVE, DIVE2)-protocols. [PDF]
Gronnier M +15 more
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Occupational Asthma Due to Subtilisin: The Power of Specific Inhalation Challenge. [PDF]
Liviero F +4 more
europepmc +1 more source
Early Detection of Asthma: Exploring Inflammatory Biomarkers in Symptomatic Adults with Normal Spirometry. [PDF]
Laroche J +11 more
europepmc +1 more source
Changes in Small Airway Physiology Measured by Impulse Oscillometry in Subjects with Allergic Asthma Following Methacholine and Inhaled Allergen Challenge. [PDF]
Stenberg H +10 more
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Seasonal Variability of the Methacholine Challenge Test
Journal of Asthma, 2009Since the intensity of some variables that influence bronchial hyper-responsiveness (BHR) varies across different seasons of the year, the percentage of positive metacholine challenge test (MCT) is theoretically subjected to seasonal variation. This study has looked at the seasonal variability of MCT among young adults with suspected asthma.The number ...
Oren, Fruchter, Mordechai, Yigla
openaire +4 more sources
The Abbreviated Methacholine Challenge Test is Safe for Children
The Journal of PediatricsTo evaluate the safety of an abbreviated methacholine challenge test (MCT) protocol in children.This prospective, observational study enrolled children aged 6 through 18 years referred for the MCT. The abbreviated protocol was initiated with a methacholine dose of 0.03 mg/ml and escalated in fourfold increments, unless the forced expiratory volume at 1
Avigdor, Hevroni +5 more
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Methacholine challenge has been proposed as a diagnostic test in situations where clinical asthma is suspected but reversible airway obstruction cannot be demonstrated spirometrically. Methacholine challenge was used in 14 patients with suspected asthma and five normal controls.
L J, Fetters, J I, Matthews
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Clinical Use of Methacholine Bronchial Challenge Testing
Southern Medical Journal, 1987Whereas the research applications have been well established, the clinical utility of bronchial challenge testing is still being defined. In 19 of 22 patients referred for testing (86%), the results of a methacholine challenge test helped to confirm a clinical suspicion of asthma or to suggest that alternative diagnoses should be investigated.
W M, Alberts, A L, Goldman
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