Results 161 to 170 of about 12,857 (207)
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Developing Alternative Delivery Systems for Methacholine Challenge Tests
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2014The two American Thoracic Society recommended aerosol delivery devices for methacholine challenge testing are both obsolete and often very difficult to acquire, leading to the test being done with a number of nonstandardized nebulizers. Of the two recommended devices, one is the English Wright nebulizer used in the 2-min tidal breathing method, and the
Allan L, Coates +2 more
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Post-Test Probability of Asthma Following Methacholine Challenge
Chest, 1990Using recently published data, a nomogram was constructed to estimate the likelihood of asthma following methacholine challenge. Based on Bayes' theorem, the nomogram makes use of the sensitivity and specificity of methacholine challenge to calculate the post-test probability of asthma once the physician makes a determination of the pretest probability,
R, Gilbert, J H, Auchincloss
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Vocal Cord Dysfunction Induced by Methacholine Challenge Testing
Chest, 2002To determine whether methacholine challenge testing (MCT) provokes vocal cord dysfunction (VCD), as evidenced by inspiratory vocal cord closure on direct laryngoscopy, and whether spirometry and flow-volume loops (FVLs) demonstrate any changes that are suggestive of VCD.Prospective, controlled study.Army medical center.Thirty-four subjects all with ...
Patrick J, Perkins, Michael J, Morris
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Methacholine Challenge Testing: Comparison of FEV1 and Airway Resistance Parameters
Respiratory Care, 2021A 20% reduction in the FEV1 is routinely used as an end point for methacholine challenge testing (MCT). Measurement of FEV1 is effort dependent, and some patients are not able to perform acceptable and repeatable forced expiration maneuvers. The goal of the present study was to investigate the diagnostic value of airway resistance measurement by forced
Tomasz, Urbankowski +1 more
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Airway Hyperresponsiveness by Methacholine Challenge Testing Following Negative Exercise Challenge
Journal of Asthma, 2004Exercise challenge testing (ECT) to diagnose exercise-induced bronchospasm has been demonstrated to be an insensitive screening test to demonstrate the presence or absence of airway hyperreactivity. Previous studies have not compared this procedure to methacholine challenge testing (MCT) in a clinical setting.To determine the frequency of positive MCT ...
Linda L, Brown +2 more
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Methacholine challenge tests results in children are season dependent
Paediatric Respiratory Reviews, 2012It is known that several parameters influence the positivity of a methacholine challenge (MCH), including a recent viral disease, allergies, and air pollution. Reports regarding the influence of the season upon the positivity of MCH are scarce. The aim of this study was to assess the percentage of positive MCH tests per season.We retrospectively ...
Leon, Joseph +3 more
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Effect of lowering Methacholine Challenge Test cutoff in children
Annals of Allergy, Asthma & Immunology, 2014The diagnosis of asthma is based on clinical judgment, history of personal or familial atopy, and testing, typically with a methacholine challenge test (MCT). Guidelines suggest a provocation concentration that caused a decrease in forced expiratory volume in 1 second of 20% (PC20) cutoff of 4 mg/mL for a positive test result.To investigate the effect ...
Ahlam, Mazi, Larry C, Lands
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Methacholine challenge tests: sample sizes required in crossover trials
Int. Journal of Clinical Pharmacology and Therapeutics, 2006Methacholine challenge testing is common for assessing the pharmacodynamic properties of anti-asthma drugs. In order to design studies and to interpret published studies, sample size calculations are essential. Unfortunately, wrong sample sizes were previously reported in the literature.
M, Neuhäuser, K H, Jöckel
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Methacholine Challenge Testing in Reserve Officer Training Corps Cadets
CHEST, 2001To determine the prevalence of positive results for methacholine challenge tests in asymptomatic Reserve Officer Training Corps (ROTC) cadets with no history of asthma.Prospective, blinded cohort comparison study.Pulmonary diseases clinic in a US Army tertiary-care medical center.One hundred three college students who were undergoing a physical ...
B J, Roth, L M, Hammers, T A, Dillard
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Predictors of methacholine challenge testing results in subjects without airflow obstruction
Journal of Asthma, 2021Methacholine challenge testing (MCT) is considered when asthma remains clinically suspected despite normal spirometry. Few studies have attempted to determine the predictive factors of MCT results. We aimed to establish which demographic data, clinical symptoms, pulmonary function testing results, and laboratory values were associated with abnormal MCT
Stephanie, Chevrier +2 more
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