Results 51 to 60 of about 3,643,521 (182)
Advanced Science, Volume 13, Issue 18, 27 March 2026.This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan +10 more
wiley +1 more source
Pharmacology of airway afferent nerve activity [PDF]
, 2001 Afferent nerves in the airways serve to regulate breathing pattern, cough, and airway autonomic neural tone. Pharmacologic agents that influence afferent nerve activity can be subclassified into compounds that modulate activity by indirect means (e.g ...
Carr Michael J, Undem Bradley J
core +2 more sources
Acute Exercise Challenge and Airway Dynamics in Youth With Sickle Cell Anemia: A Multicenter Study
American Journal of Hematology, Volume 101, Issue 3, Page 418-426, March 2026.Changes in airway dynamics in children with sickle cell anemia after maximal cardiopulmonary exercise testing and a controlled intensity interval excercise challenge. ABSTRACT Sickle cell anemia (SCA) leads to reduced physical functioning and cardiopulmonary fitness. Prior studies suggest that airway hyperresponsiveness to bronchoprovocation testing is
Robyn T. Cohen +9 more
wiley +1 more source
Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma.
BMB Reports, 2012 Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane), belonging to a family of natural compounds that are abundant in broccoli, has received significant therapeutic interest in recent years.
Jun Ho Park +11 more
semanticscholar +1 more source
Role of cyclooxygenase in the vascular response to locally delivered acetylcholine in Caucasian and African descent individuals [PDF]
, 2017 This is an accepted manuscript of an article published by Elsevier in Microvascular Research on 17/01/2017, available online: https://doi.org/10.1016/j.mvr.2017.01.005 The accepted version of the publication may differ from the final published version.©
Eglin, CM +3 more
core +3 more sources
iMetaOmics, Volume 3, Issue 1, March 2026.Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley +1 more source
Common respiratory diseases. [PDF]
, 2010 The self-medication phenomenon in upper respiratory tract infections, rhinosinusitis, asthma, and chronic obstructive pulmonary disease are significant and will continue to increase.
Kilgore, David, Najm, Wadie
core
New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]
, 2018 Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A. +2 more
core +2 more sources
Acepromazine Reduces Airway Contraction in a Murine Model of Asthma
Clinical and Experimental Pharmacology and Physiology, Volume 53, Issue 3, March 2026.ABSTRACT Acepromazine (ACP) is one of the most used sedatives in veterinary medicine, and its cardiovascular effects are well documented. In contrast, its effects on the respiratory system remain less well understood, particularly in the context of assessment of respiratory mechanics in murine models of asthma, where its use has become more common in ...
Alembert Lino‐Alvarado +6 more
wiley +1 more source
Allergy, Volume 81, Issue 3, Page 734-749, March 2026.This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco +38 more
wiley +1 more source