Results 31 to 40 of about 3,643,521 (182)

Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma [PDF]

, 2010
Background Exposure to chlorine (Cl2) causes airway injury, characterized by oxidative damage, an influx of inflammatory cells and airway hyperresponsiveness. We hypothesized that Cl2-induced airway injury may be attenuated by antioxidant treatment, even
Toby K McGovern, William S Powell, Brian J Day, Carl W White, Karuthapillai Govindaraju, Harry Karmouty-Quintana, Normand Lavoie, JuJing Tan, James G Martin   +8 more
core   +2 more sources

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Orally administered yeast‐derived β‐glucan alleviates mast cell‐dependent airway hyperresponsiveness and inflammation in a murine model of asthma

Immunity, Inflammation and Disease
Background Particulate β‐glucans (WGP) are natural compounds with regulatory roles in various biological processes, including tumorigenesis and inflammatory diseases such as allergic asthma.
Jianzhou Zheng, Yu Bai, Lei Xia, Xiao Sun, Jie Pan, Shizhong Wang, Chunjian Qi   +6 more
doaj   +1 more source

The relaxant effect of Ferula assafoetida on smooth muscles and the possible mechanisms [PDF]

, 2015
Asafoetida (Ferula asafoetida) an oleo-gum-resin belongs to the Apiaceae family which obtained from the living underground rhizome or tap roots of the plant. F.
Boskabady, M.H., Khazdair, M.R.
core  

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Identifying phenotypes and factors impacting outcomes in older adults with asthma: A research protocol and recruitment results

Research in Nursing and Health, 2018
Success in testing research outcomes requires identification of effective recruitment strategies in the targeted population. In this paper, we present the protocol for our NIH-funded study as well as success rates for the various recruitment strategies ...
B. Polivka, R. Folz, J. Myers, Russell Barnett, D. Antimisiaris, Anna Jorayeva, Bryan L. Beatty   +6 more
semanticscholar   +1 more source

EAACI position paper on occupational rhinitis [PDF]

, 2009
The present document is the result of a consensus reached by a panel of experts from European and non-European countries on Occupational Rhinitis (OR), a disease of emerging relevance which has received little attention in comparison to occupational ...
J Bousquet, AM Vignola, G Passalacqua, J Bousquet, A Togias, C Bachert, G Passalacqua, P Demoly, A Siracusa, D Gautrin, J Walusiak, DC Christiani, ML Ng, DY Wang, R Castano, JE Salvaggio, MS Dykewicz, European Commission, RG Slavin, J Hellgren, T Storaas, JL Malo, O Vandenplas, IL Bernstein, RA Nathan, PH Howarth, D Shusterman, R Castano, SG Johansson, M Chan-Yeung, WJ Meggs, C Leroyer, CD Hoffman, SM Brooks, WJ Meggs, R Castano, P Cullinan, F Rodier, P Cullinan, D Gautrin, D Chloros, J Hellgren, T Kraus, RJ Laumbach, D Shusterman, D Shusterman, DJ Shusterman, D Shusterman, D Shusterman, M Hytonen, P Ruoppi, S Archambault, A Draper, D Heederik, A Hollander, AW Musk, R Houba, V Liebers, R Houba, P Cullinan, D Gautrin, G de Meer, J Walusiak, MJ Schumacher, MF Beeson, CE Mapp, A Siracusa, GD Nielsen, A Siracusa, D Gautrin, B Leynaert, GJ Braunstahl, JL Malo, O Vandenplas, NJ Gross, G Cortona, LC Grammer, X Munoz, G Moscato, A Karjalainen, L Elliott, J Bousquet, P Demoly, DI Bernstein, L Malm, L Malm, PA Clement, R Starling-Schwanz, AS Jones, M Holmstrom, VJ Lund, RW Clarke, Y Larivee, T Pirila, L Airaksinen, G Scadding, G Ciprandi, VM Struben, RG Gerth van Wijk, F Marquez, R Gerth van Wijk, D Plavec, JP Braat, A Togias, SM Walden, FM Baroody, H Klementsson, AM Sanico, A Renstrom, P Cullinan, A Cristaudo, A Krakowiak, M Hytonen, LI Litvyakova, K Rajakulasingam, J Gosepath, G Melillo, C Bachert, A Linder, B Lebel, P Gorski, G Moscato, O Vandenplas, AJ Slovak, N Laoprasert, SS Braman, C Laprise, K Boutet, C Porsbjerg, S Guerra, PL Piirila, O Vandenplas, R Merget, DI Bernstein, RJ Salib, J Bousquet, J Sastre, DC Malone, AW Law, B Schramm, R Gupta, BP Yawn, NF Ray, D Price, IM Cockburn, TM Gilmore, P Fireman, J Crystal-Peters, LP Hanrahan, PD Blanc, P Demoly, J Brisman, J Bousquet, EO Meltzer, R Gerth van Wijk, GC Groenewoud, CP Juniper, MK Schweigert, K Sarlo, EG Hugues, PA Botham, R Fisher, S Gordon, D Levy, SM Tarlo, MJ Saary, H Allmers, U Latza, PA Eggleston, S Quirce, D Heederik, P Cullinan, X Baur, M Chan-Yeung, P Cullinan, PJ Nicholson, SM Tarlo, J Walusiak, B Nguyen, D Gautrin, D Gautrin, PJ Nicholson, PF Gannon, R Merget, L Grammer, T de Graaf-in 't Veld, T Young, BA Stuck, D Leger, EF Juniper, EF Juniper, MS Benninger, BA Senior, W Fokkens, SL Spector, W Fokkens, J Bousquet, PJ Bousquet, C Bachert, G Block, O Vandenplas, O Vandenplas, KK Heldal, M Ahman, M Ahman, RM Naclerio, C Palczynski, M Raulf-Heimsoth, J Walusiak, C Palczynski, T Wittczak, JD Boot, M Chan-Yeung, S Juliusson, E Crimi, G Ciprandi   +215 more
core   +2 more sources

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, Volume 16, Issue 4, Page 369-379, April 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source

Heart rate variability in association with frequent use of household sprays and scented products in SAPALDIA [PDF]

, 2012
Background: Household cleaning products are associated with adverse respiratory health outcomes, but the cardiovascular health effects are largely unknown.Objective: We determined if long-term use of household sprays and scented products at home was ...
Adam, M., Barthelemy, J. C., Carballo, D., Gaspoz, J. M., Künzli, N., Mehta, A. J., Probst-Hensch, N., Rochat, T., Sapaldia, Team, Schaffner, E., Schindler, C., Schwartz, J., Zock, J. P.   +12 more
core   +1 more source