Results 151 to 160 of about 58,733 (293)

Comparative Toxicological Profiling Reveals Divergent Redox, Mitochondrial, and Cellular Toxicity to Structurally Diverse Opioids. [PDF]

J Xenobiot
Pizent A, Zandona A, Jurič A, Tariba Lovaković B, Rašić D, Kopjar N, Vuković K, Katalinić M, Rešić A, Canjuga I, Vrdoljak AL, Karačonji IB.   +11 more
europepmc   +1 more source

Decision-Making Performance and Block-Wise Trajectories in Gambling Disorder and Opioid Use Disorder Using the Iowa Gambling Task. [PDF]

Brain Sci
Gorzelańczyk EJ, Kawala-Sterniuk A, Laskowska E, Kamiński P, Walecki P.   +4 more
europepmc   +1 more source

Cheek tooth extraction in geriatric versus non‐geriatric horses

Equine Veterinary Journal, Volume 58, Issue 6, Page 1707-1716, November 2026.
Abstract Background Age‐related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population.
Elias Mair, Omid Nekouei, Patricia Trummer‐Schug, Rhea Haralambus, Nora Mareike Biermann   +4 more
wiley   +1 more source

Intraoperative Methadone for Postoperative Pain Control in Living Donor Hepatectomy. [PDF]

J Transplant
Seibert A, Puri D, Whong Z, Kim B, Alsaadawi R, Kang L, Kim C, Lee SD, Kumaran V, Pancholia S, Navarrete S.   +10 more
europepmc   +1 more source

Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation. [PDF]

PLoS One
de Hoop-Sommen MA, Alozai S, Gijsen VMGJ, van der Zanden TM, Akinbi HT, Mizuno T, Vinks AA, Greupink R, de Wildt SN.   +8 more
europepmc   +1 more source

How more people died on methadone than heroin in Ireland.

, 2014
More methadone users than heroin users died in one year in Ireland, according to new figures. The Health Research Board found that 113 methadone users died of an overdose in 2011, almost double the number of heroin users.

core  

Society for Maternal‐Fetal Medicine Special Statement: Guidance to reduce racial disparities in substance use screening and biological testing in pregnancy at the delivery admission

Pregnancy, Volume 2, Issue 6, November 2026.
Abstract Substance use complicates upward of 10% of US pregnancies. The Society for Maternal‐Fetal Medicine, the American College of Obstetricians and Gynecologists, and the American Society of Addiction Medicine have jointly recommended universal screening for substance use during pregnancy using a validated tool, without recommending universal ...
Society for Maternal‐Fetal Medicine (SMFM), Jennifer J. M. Cate, Samuel T. Bauer, Niraj R. Chavan, Marc Parrish, Jessica Peterson, Dena Goffman, Christina Davidson, SMFM Patient Safety and Quality Committee   +8 more
wiley   +1 more source

Target‐Engagement Prediction From Molecular Structure, In Vitro and Animal Data: A Tutorial for Early Assessment of Clinical Drug Exposure and Therapeutic/Adverse Potential Using the ANDROMEDA and PLATO Software on the InSilicoTrials Platform

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT The target‐engagement predictor, implemented within the InSilicoTrials cloud‐based, AI‐powered platform for model‐informed drug discovery and development, enables early exploration of time‐dependent pharmacological responses. Predictions can be generated using inputs ranging from molecular structure to in vitro, animal, and clinical data ...
Niccolò Totis, Fianne Sips, Simona Catozzi, Marc‐Antonio Bisotti, Pauline Bambury, Sofia Stathopoulos, Vincenzo Carbone, Luca Emili, Mario Torchia, Valentina Belgiovine, Fulvio Ciriaco, Orazio Nicolotti, Urban Fagerholm, Candice N. Baker, J. Matthew Mahoney, Daniel Röshammar, on behalf of the CARDIOVERSE Project   +16 more
wiley   +1 more source

Does Methadone Affect <i>TERT</i> Expression and Telomere Length? [PDF]

Balkan Med J
Omidpanah N, Saadat M.
europepmc   +1 more source

Primary Erythrocytosis (Polycythaemia) in a Neutered Male Dog Presenting With Right Hindlimb Lameness

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A young dog presented with progressive unilateral hindlimb lameness and marked erythrocytosis. Diagnostic investigations excluded secondary causes and confirmed primary erythrocytosis. Targeted vascular ultrasonography identified a right external iliac venous thrombus as the suspected cause of lameness.
Robyn Belch, Perrine Henry, Marisa Ferreira, Albert Aguilera Padros, Maria Lazaro Munoz, Ben Lloyd‐Bradley, Ingrid Isaac, Efa Llewellyn, Aran Nagendran   +8 more
wiley   +1 more source