Results 191 to 200 of about 51,765 (292)

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, Volume 38, Issue 8, Page 442-452, August 2026.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

An opioid-withholding human laboratory paradigm during opioid agonist treatment for opioid use disorder and chronic pain: Phase- and dose-dependent effects of cannabidiol. [PDF]

Neuropsychopharmacology
P A Costa G, Sofuoglu M, Compton P, Ranganathan M, Pittman B, De Aquino JP.   +5 more
europepmc   +1 more source

Impact of Antiviral Therapy Scale‐Up Among People Who Inject Drugs in Scotland: Regional Evidence of Hepatitis C Virus Elimination

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background Expansion of highly effective direct‐acting antiviral (DAA) treatment for people who inject drugs (PWID) is regarded as essential to achieve hepatitis C virus (HCV) elimination. A decade since the introduction of DAA treatment, we aimed to assess its roll‐out and associated impact in reducing HCV prevalence among PWID in Scotland ...
Norah E. Palmateer, Pantelis Samartsidis, Christopher Biggam, Andrew McAuley, Scott A. McDonald, John Dillon, Stephen T. Barclay, Samantha J. Shepherd, Rory N. Gunson, Monica Desai, Duncan McCormick, Daniela De Angelis, Matthew Hickman, Sharon J. Hutchinson   +13 more
wiley   +1 more source

‘We All Try to Imagine What It's Like for Someone to Be Dependent’: Attitudes Towards Drug Users Among Medical Students in the United Kingdom and Its Impact on Their Professional Identity Formation

The Clinical Teacher, Volume 23, Issue 4, August 2026.
ABSTRACT Background Evidence suggests that some doctors and medical students hold stigmatising attitudes towards drug users. This area remains underexplored in the United Kingdom (UK), and current medical students' attitudes to drug users are unknown.
Holly Melvin, Dilmini Karunaratne, Jason W. Boland   +2 more
wiley   +1 more source

Integrating Pharmacovigilance Data Mining and Mendelian Randomization to Identify Risk Profiles and Causal Targets of Opioid-Induced Delirium. [PDF]

CNS Neurosci Ther
Chen X, Liu Y, Zhu M, Chen X, Liu F, Jin J, Jiang Z, Qian B, Li F.   +8 more
europepmc   +1 more source

Technical note on an ovine model to study biomedical implants intended for maxillofacial reconstruction

Veterinary Surgery, Volume 55, Issue 6, Page 1152-1164, August 2026.
Abstract Objective To describe a repeated‐measures model permitting evaluation of up to four implants intended for maxillofacial applications in sheep. Animals Two‐year‐old Merino wethers (n = 5). Methods A retromandibular subparotid approach was developed through anatomical study of atlases, predissected models and cadaveric experiments.
Reza Sanaei, Ayda Farhoudi, Babatunde A. Ayodele, George Dimitroulis, Christina M. Murray, Helen M. Davies, Alastair J. Sloan, Charles N. Pagel   +7 more
wiley   +1 more source

Temporary transarticular stabilization with locking compression plate for the treatment of traumatic glenohumeral luxation in 10 dogs

Veterinary Surgery, Volume 55, Issue 6, Page 1143-1151, August 2026.
Abstract Objective The aim of this study was to describe the surgical technique, and the short to medium clinical outcome of dogs treated with temporary glenohumeral joint (GHJ) stabilization following traumatic luxation. Study Design Short case series.
Alexandros Bourbos, Francesco Piana, Alex Belch, Luca Vezzoni   +3 more
wiley   +1 more source

Intravenous paracetamol does not have significant opioid‐sparing effects when used as part of a multimodal analgesic protocol in dogs undergoing elective orthopaedic surgery

Veterinary Record, Volume 199, Issue 1, Page e13-e20, 4/11 July 2026.
Abstract Background Data evaluating paracetamol combined with NSAIDs in dogs are scarce. Results of clinical studies in dogs investigating intravenous paracetamol vary. Methods Dogs were randomised to either receive 10 mg/kg paracetamol intravenously after induction of anaesthesia and every 8 hours during hospitalisation (test) or not (control).
Robin Stallard, Julia Deutsch, Joanna Murrell   +2 more
wiley   +1 more source

Investigating Changes in Liver Enzyme Levels in Patients With Acute Methadone Poisoning. [PDF]

J Toxicol
Mousavi SR, Ivari MA, Khazaei AR, Gharibi S, Vakili V, Rozmina S, Mousavi SA, Rafati SS.   +7 more
europepmc   +1 more source

Prenatal exposure to buprenorphine or methadone and adverse neurodevelopmental outcomes: population based cohort study.

BMJ
Friedrich S, Huybrechts KF, Straub L, Hernandez-Diaz S, Zhu Y, Hahn G, Mogun H, Jones HE, Connery HS, Davis JM, Gray KJ, Lester B, Terplan M, Bateman BT.   +13 more
europepmc   +1 more source