Results 271 to 280 of about 118,303 (321)

Trends in Methadone Use for Pain and Opioid Use Disorder Among Medicaid Enrollees.

JAMA Health Forum
Hsu YS, Thakrar AP, Leonard CE, Lowenstein M, Brensinger CM, Bilker WB, Bogar KF, Hennessy S.   +7 more
europepmc   +1 more source

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Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies.

Lancet psychiatry, 2023
BACKGROUND Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment.
L. Degenhardt, Brodie Clark, Georgina Macpherson, Oscar Leppan, S. Nielsen, E. Zahra, B. Larance, J. Kimber, Daniel Martino-Burke, M. Hickman, Michael Farrell   +10 more
semanticscholar   +1 more source

The impact of relaxation of methadone take-home protocols on treatment outcomes in the COVID-19 era

The American Journal of Drug and Alcohol Abuse, 2021
Background Background: In response to the COVID-19 pandemic, the US Substance Abuse and Mental Health Services Administration (SAMHSA) allowed for an increase in methadone take-home doses for the treatment of Opioid Use Disorder (OUD) in March 2020 ...
O. Amram, S. Amiri, Victoria Panwala, Robert B. Lutz, P. J. Joudrey, E. Socias   +5 more
semanticscholar   +1 more source

Methadone

American Journal of Hospice and Palliative Medicine®, 2008
Methadone hydrochloride is an old drug that has been in vogue off and on. It has complex pharmacodynamics and can be potentially fatal in inexperienced settings. Drug switching from an opioid to methadone or vice versa requires knowledge of equianalgesic dosing.
Chhabra, Shalini, Bull, Janet
openaire   +4 more sources

Methadone—Disulfiram Interaction During Methadone Maintenance

The Journal of Clinical Pharmacology, 1980
In an attempt to characterize a possible drug interaction between methadone and disulfiram, 500 mg/day insulfiram was administered orally for seven days to seven subjects on methadone maintenance. Plasma methadone concentrations and urinary excretion of methadone and its pyrrolidine and pyrrolidone metabolites were measured and subjective symptoms of ...
T G, Tong, N L, Benowitz, M J, Kreek
openaire   +2 more sources

Disposition of methadone in methadone maintenance

Clinical Pharmacology & Therapeutics, 1975
Six detoxified opiate addicts housed in a closed metabolic ward received methadone in stepwise increasing doses of 10, 20, 40, and 80 mg/day during 1 month. Four were given 14C‐methadone at the lowest dose and again at the highest dose. Of the subjects receiving radiomethadone, 2 excreted the major part of the radioactivity in urine and 2 about equally
E, Anggård, L M, Gunne, J, Homstrand, R E, McMahon, C G, Sandberg, H R, Sullivan   +5 more
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Methadone and methadone metabolites in postmortem specimens

Forensic Science, Medicine, and Pathology, 2008
We have determined drug/metabolite concentrations and ratios of methadone (METH) to two of its metabolites (EDDP, 2-ethylidene-1, 5-dimethyl-3, 3-diphenylpyrrolidine; and EMDP, 2-ethyl-5-methyl-3,3-diphenylpyrroline) in postmortem peripheral blood and liver tissue by liquid chromatography/tandem mass spectrometry.
Terry J, Danielson, Ashraf, Mozayani, Luis A, Sanchez   +2 more
openaire   +2 more sources