Results 111 to 120 of about 53,967 (290)

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Middle School Students' Learning of the Impact of Methamphetamine Abuse on the Brain

, 2009
In respond to the solicitation of National Institute on Drug Use (NIDA) (NIDA, 2006) for the “Development of a Virtual Reality Environment for Teaching about the Impact of Drug Abuse on the Brain†, a virtual brain exhibit was developed by the ...
Cheng, Meng-Tzu
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A detailed analysis of the effects of methamphetamine on schedule-controlled responding in pigeons [PDF]

, 2009
In behavioral pharmacology, overall response rate is the measure most often used to study the effects of drugs on an animal’s ongoing operant behavior.
NC DOCKS at The University of North Carolina Wilmington, Bennet, J. Adam   +1 more
core  

Has Australia lost control of its tobacco and nicotine markets?

Addiction, EarlyView.
Abstract Background Australia has adopted two policies that the World Health Organization (WHO) recommends as best practice for tobacco control: it has steeply increased tobacco taxes since 2010 and only allowed access to nicotine vapes for medical use.
Ron Borland, James Martin, Edward Jegasothy, Ben Youdan, Wayne Hall   +4 more
wiley   +1 more source

Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate. [PDF]

Chirality
Methamphetamine is an amphetamine‐type stimulant characterized by a single stereogenic center, resulting in two enantiomers, (R)‐(−)‐methamphetamine and (S)‐(+)‐methamphetamine, with distinct biological and pharmacological profiles. These forms exhibit differences in central nervous system activity, metabolism, excretion, and overall physiological ...
do Espírito Santo LP, de Carvalho RL, Sad JA, Dos Santos PHC, Domingues RS, de Azevedo Cardoso G, Enes KB, Goulart GAC, de Castro Lourenço das Neves M, de Fátima Â.   +9 more
europepmc   +2 more sources

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson, Thomas Parkhouse, Chloe Burke, Monika Halicka, Jennifer C. Palmer, Hend Gabr, Rebecca Wilson, Katie E. Webster, Francesca Spiga, Sarah Dawson, Deborah M. Caldwell, Jennifer Scott, Julian P. T. Higgins, Jelena Savović   +13 more
wiley   +1 more source

Effect of Four Weeks of Aerobic Exercise and Berberine Supplementation on the Expression of Dopamine 5 Receptor and Poly (Adenosin Diphosphat [ADP]-Ribose) Polymerase Genes in the Heart Tissue of Methamphetamine-Exposed Rats [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: Methamphetamine is a highly addictive drug associated with severe psychosocial consequences and is extensively abused. This study aimed to determine the effects of four weeks of aerobic exercise and berberine supplementation on ...
Zahra Aghajani, Somayeh Rajabi, Sayyed-Javad Ziaolhagh   +2 more
doaj  

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

Addiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien, Lisa‐Marie Greenwood, Arush Honnedevasthana Arun, Isabella Goodwin, Anastasia Paloubis, Tribikram Thapa Rana, Marianna Quinones Valera, Eugene McTavish, Gabrielle Abbott, Suraya Dunsford, Antonio Verdejo‐Garcia, Jessica Ramamurthy, Mark M. Schira, Nadia Solowij, Chao Suo, Valentina Lorenzetti   +15 more
wiley   +1 more source

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

Addiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam, Mohammad Karamouzian, Michael John Milloy, Carmen Verdicchio, Eric C. Sayre, Kanna Hayashi, Thomas Kerr, Kora DeBeck   +7 more
wiley   +1 more source

Int J Drug Policy [PDF]

Introduction:In the United States, methamphetamine use is increasing and the context of its use has changed, with reports of illicitly manufactured fentanyl being mixed with methamphetamine (either deliberately or inadvertently).

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