Results 211 to 220 of about 53,967 (290)

Research Progress on the Regulatory Mechanisms of Gut Microbiota in Methamphetamine Addiction and Targeted Interventions

open access: yesAddiction Biology, Volume 31, Issue 9, September 2026.
METH induces gut dysbiosis with increased proinflammatory and decreased beneficial bacteria, impairs mucosal barrier with reduced SCFAs/Occludin and increased permeability, leading to endotoxin leakage. This activates HPA axis, vagus‐CNS pathways, oxidative stress, and gut‐testis axis disturbance, all synergistically causing neurotoxicity, addiction ...
Jihao Yang, Yishuang Dai, Jia Li
wiley   +1 more source

Aerobic exercise for substance use disorders: therapeutic effects and underlying mechanisms. [PDF]

open access: yesFront Med (Lausanne)
Liu QQ   +7 more
europepmc   +1 more source

Systemic Everolimus Does Not Block the Incubation of Methamphetamine‐Craving: A Dose–Response Study

open access: yesAddiction Biology, Volume 31, Issue 9, September 2026.
Oral pretreatment with the mTOR inhibitor Everolimus failed to block incubated methamphetamine‐seeking in a rat model, even at doses as high as 10 mg/kg. Further, neither methamphetamine experience nor Everolimus pretreatment altered protein indices of mTOR signaling with the prefrontal cortex.
Fernando J. Cano   +12 more
wiley   +1 more source

Acquisition‐Recruited and MOR‐Expressing Striatal dMSNs Differentially Regulate Extinction and Cue‐Induced Relapse of Alcohol Seeking

open access: yesAddiction Biology, Volume 31, Issue 9, September 2026.
Extinction training reduced cue‐induced alcohol seeking and reactivation of acquisition‐recruited dorsomedial striatal dMSN ensembles. Maintaining acquisition‐ensemble activity during extinction increased later relapse, whereas activating MOR‐expressing, striosome‐enriched dMSNs facilitated extinction‐related behavioural change and reduced subsequent ...
Xueyi Xie, Xuehua Wang, Jun Wang
wiley   +1 more source

A call for action: Closing the evidence gap in management of stimulant‐induced psychosis

open access: yesAddiction, Volume 121, Issue 9, Page 2275-2283, September 2026.
Abstract Background Stimulant‐induced psychosis (StIP) is emerging as one of most pressing health challenges. Over the past two decades, stimulant‐related harms and psychiatric care demands have risen sharply. Individuals with StIP often present with severe agitation and high suicide risk, and up to half progress to chronic psychotic illness within two
Anne Bouthillier   +3 more
wiley   +1 more source

Multiyear Wastewater Monitoring of High-Risk Substances Surrounding an Annual Electronic Dance Music Festival, Las Vegas, Nevada, USA, 2023-2025: Surveillance Study. [PDF]

open access: yesJMIR Public Health Surveill
Gerrity D   +9 more
europepmc   +1 more source

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