Results 71 to 80 of about 1,119,251 (284)

Supplementation with a mixture of whole rice bran and crude glycerin on metabolic responses and performance of primiparous beef cows

Revista Brasileira de Zootecnia, 2016
- This study investigated the effect of a supplement containing whole rice bran and crude glycerin for 21 days before mating on metabolic, productive, and reproductive responses of 28 primiparous suckling beef cows.
Juan Manuel Clariget, Lorena Román, Mauricio Karlen, Andrea Álvarez-Oxiley, Carlos López-Mazz, Raquel Pérez-Clariget   +5 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Test Results for a Novel 20 kW Two-Phase Pumped Cooling System for Aerospace Applications

Aerospace
In the EU-funded BRAVA project, technologies for a fuel cell-based power generation system for aviation are being developed. In this paper, the test results for a demonstrator of a novel two-phase pumped cooling system with 20 kW cooling capacity are ...
Henk Jan van Gerner, Tim Luten, Sigurd Scholten, Georg Mühlthaler, Marcus-Benedict Buntz   +4 more
doaj   +1 more source

Sulfur vacancy-rich MoS2 as a catalyst for the hydrogenation of CO2 to methanol

Nature Catalysis, 2021
Jingting Hu, Liang Yu, Jiao Deng, Yong Wang, K. Cheng, Chao Ma, Qinghong Zhang, Wu Wen, Shengsheng Yu, Yang Pan, Jiuzhong Yang, Hao Ma, F. Qi, Yongke Wang, Yanping Zheng, Mingshu Chen, Rui Huang, Shuhong Zhang, Zhenchao Zhao, Jun Mao, Xiangyu Meng, Qi Ji, Guangjin Hou, Xiuwen Han, X. Bao, Ye Wang, Dehui Deng   +26 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Improving Net Energy Efficiency of Dimethyl Ether Production Process by Methanol Dehydration

Journal of Chemical Engineering Research Progress
Dimethyl ether (DME) is a source of fuel that produces clean energy for the future. Methanol can be used as a raw material for the manufacture of DME as a natural gas that is treated for synthesis.
Astrid Eka Permatasari, Syalaisa Nanda Syabila, Hly Tyas Ajeng Kartika Dewi, Rufaidah Nilam Zahra   +3 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source