Results 51 to 60 of about 709,754 (279)

Predictions and measurements of spark-ignition engine characteristics using ammonia and other fuels [PDF]

, 1988
PhDThe project reported here involves the development of a computer model for determining the characteristics of a spark-ignition engine. The model incorporates detailed consideration of the combustion process -and includes calculations for heat ...
Mozafari-Varnusfadrani, Aliasghar
core   +4 more sources

Prediction of Performance and Emission of Gasoline Engine Fueled with a Gasoline-Ethanol-Methanol Mixture Using One Dimensional Engine Modelling Based on Engine Test Results

Automotive Experiences
The depletion of petroleum reserves as the basic raw material for gasoline production has driven studies into alternative fuels. One of the alternative fuels is alcohol, both ethanol and methanol.
Rudi Cahyo Nugroho, Respatya Teguh Soewono, Ade Kurniawan, Muhammad Ma'ruf, Mohammad Amanta Kumala Sakti, Suherman Mukti, Abid Paripurna Fuadi, Bagus Anang Nugroho   +7 more
doaj   +1 more source

Dynamic pressure control and GA-based PID optimization study of fuel supply system for methanol-fueled ships [PDF]

International Journal of Fluid Engineering
The search for clean alternative fuels to replace conventional high-emission marine fuels is a pressing issue in the context of carbon neutrality. Methanol, owing to its ability to be stored at ambient temperatures, is considered one of the promising ...
Changan Xu, Chaojun Huang, Hongbo Qian, Deng Wang, Aiguo Yu, Xiaojiu Tang, Liang Hao, Jianlu Zhu, Shusen Zhang   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Evaluation of the Effects of Methanol and Ethanol Additions on Performance and Emissions in a Spark Plug Ignition Engine Fueled with Gasoline

International Journal of Automotive Science and Technology, 2022
The aim of this experimental study was to investigate the effect of addition of methanol and ethanol (5% - 10% and 15%) as a fuel at low rates to gasoline fuel against performance, and emissions characteristics.
İlker Örs, Halil Erdi Gülcan, Bahar Sayın Kul, Savaş Yelbey, Murat Ciniviz   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Methanol as a fuel for internal combustion engines

Progress in Energy and Combustion Science, 2019
Abstract Transportation of people and goods largely relies on the use of fossil hydrocarbons, contributing to global warming and problems with local air quality. There are a number of alternatives to fossil fuels that can avoid a net carbon emission and can also decrease pollutant emissions. However, many have significant difficulty in competing with
Sebastian Verhelst, James WG Turner, Louis Sileghem, Jeroen Vancoillie   +3 more
openaire   +4 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Numerical Study on a Diesel/Dissociated Methanol Gas Compression Ignition Engine with Exhaust Gas Recirculation

Applied Sciences, 2023
Hydrogen is the most promising alternative fuel in the field of engines. Exhaust heat-assisted methanol dissociation is an attractive approach for generating hydrogen.
Bo Li, Yihua Chen, Fei Zhong, Hao Xu
doaj   +1 more source