Results 21 to 30 of about 900,987 (240)

Pyrazole-Derived Antibacterial Compounds Effectively Treat Methicillin-Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase. [PDF]

Adv Sci (Weinh)
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Yang X, Cao X, Dai L, Yang F, Wang J, Ma Y, Bu T, Gong Z, Liu X, Bai C, Miao X, Shang X.   +11 more
europepmc   +2 more sources

Methicillin-resistant and methicillin-susceptible community-acquired Staphylococcus aureus infection among children

Brazilian Journal of Infectious Diseases, 2013
Methicillin-resistant Staphylococcus aureus has emerged as a pathogen associated with community-acquired infections worldwide. We report the spectrum of community-acquired S.
Renata Tavares Gomes, Ticiana Goyanna Lyra, Noraney Nunes Alves, Renilza Menezes Caldas, Maria-Goreth Barberino, Cristiana Maria Nascimento-Carvalho   +5 more
doaj   +3 more sources

Nasal Carriage Rate of Methicillin Resistant Staphylococcus aureus among Health Care Workers at a Tertiary Care Hospital in Kathmandu, Nepal

Journal of Nepal Health Research Council, 2017
Background: Methicillin-resistant Staphylococcus aureus is one of the most common causes of nosocomial infections. Due to its multidrug resistant nature; infections due to Methicillin-resistant Staphylococcus aureus are often very difficult to treat ...
Sabita Khatri, Narayan Dutt Pant, Raju Bhandari, Krishma Laxmi Shrestha, Chandrika D Shrestha, Nabaraj Adhikari, Asia Poudel   +6 more
doaj   +1 more source

Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection in dogs and cats: a case-control study. [PDF]

, 2010
Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection in dogs and cats were investigated in an unmatched case-control study. A total of 197 animals from 150 veterinary practices across the United Kingdom was enrolled, including ...
Pfeiffer, Dirk Udo, Mick Rich, Soares Magalhães, RJ, Soares Magalhaes, Ricardo Jorge, Lindsay, Jodi, Lindsay, J, Lloyd, David Hugh, Larry Roberts, Loeffler, A, St George's, Lindsay, J A, Rich, M, Queensland, Australia, Pfeiffer, D U, Loeffler, Anette, Smith, H, Teringie SA, Australia, Smith, Heather, Soares-Magalhaes, R J, Lloyd, D H, Lloyd, DH, Roberts, Larry, Ricardo Jorge Soares Magalhães, Heather Smith, Rich, Mick, Anette Loeffler, Jodi Lindsay, David Hugh Lloyd, Dirk Udo Pfeiffer, Pfeiffer, DU, IDEXX Labs, Roberts, L   +31 more
core   +1 more source

Treatment procedures and associated medical costs of methicillin-resistant infection in Japan: A retrospective analysis using a database of Japanese employment-based health insurance

SAGE Open Medicine, 2019
Objectives: This study aimed to determine the patient characteristics, treatment procedures, and medical costs of methicillin-resistant Staphylococcus aureus infections in clinical practice in Japan.
Akira Yuasa, Tatsunori Murata, Keiji Imai, Yuji Yamamoto, Yoko Fujimoto   +4 more
doaj   +1 more source

Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus, Sequence Type 239 (TW) [PDF]

, 2010
The Sanger Institute is core funded by the Wellcome Trust. Funding for the sequencing of the TW20 genome was provided by Guy’s and St. Thomas’ Charity. J.D.E.
Edgeworth, Jonathan D., Quail, MA, Bentley, SD, Quail, Michael A., Parkhill, Julian, Corton, C, Parkhill, J, Lindsay, JA, Lindsay, Jodi A., Edgeworth, JD, Pathak, Smriti, Batra, R, Pathak, S, Bentley, Stephen D., Holden, MT, Holden, Matthew T. G., Cockfield, Joshua D., Batra, Rahul, Cockfield, JD, Corton, Craig   +19 more
core   +1 more source

Predominance of Methicillin Resistant Staphylococcus Aureus -ST88 and New ST1797 causing Wound Infection and Abscesses. [PDF]

, 2012
Although there has been a worldwide emergence and spread of methicillin-resistant Staphylococcus aureus (MRSA), little is known about the molecular epidemiology of MRSA in Tanzania.
Kamugisha, Erasmus, Lyamuya, Eligius F, Claus, Heike, Tappe, Dennis, Lyamuya, Eligius F., Moremi, Nyambura, Mshana, Stephen E., Kataraihya, Johannes B., Vogel, Ulrich, Mshana, Stephen E, Kataraihya, Johannes   +10 more
core   +1 more source

Evaluation of spa-typing of methicillin-resistant Staphylococcus aureus using high-resolution melting analysis [PDF]

, 2015
OBJECTIVE: spa-typing of methicillin-resistant Staphylococcus aureus (MRSA) has been widely used in clinical diagnostics and epidemiological studies. We aimed to evaluate high-resolution melting (HRM) as a rapid and cost effective method, to replace DNA ...
Gunnar Sandstrom, Waleed Mazi, Vartul Sangal, Yu, J, Saeed, Amir, Sandstrom, Gunnar, Sangal, Vartul, Sangal, V, Sandstom, Gunnar, Amir Saeed, Mazi, W,, Jun Yu, Sandstrom, G, Saeed, A,, Mazi, Waleed, Yu, Jun   +15 more
core   +1 more source

Combinations of β-lactam or aminoglycoside antibiotics with plectasin are synergistic against methicillin-sensitive and methicillin-resistant Staphylococcus aureus. [PDF]

, 2015
Bacterial infections remain the leading killer worldwide which is worsened by the continuous emergence of antibiotic resistance. In particular, methicillin-sensitive (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) are prevalent and the ...
Coates Anthony, Alexander Liu (249396), Anthony Coates (362975), Kearns Angela, Yanmin Hu, Hu Yanmin, Vaudrey, J, Christiana Moigboi, Brigita Vaiciunaite, Angela Kearns (225395), Anthony Coates, James Vaudrey (693517), Christiana Moigboi (693519), Sharla M McTavish, Vaudrey James, Vaiciunaite Brigita, Sharla M. McTavish (693520), Liu Alexander, McTavish Sharla M., Vaiciunaite, B, McTavish, SM, Alexander Liu, Yanmin Hu (155376), Hu, Y, Moigboi, C, Moigboi Christiana, Kearns, A, Liu, A, Angela Kearns, James Vaudrey, Coates, A, Brigita Vaiciunaite (693518)   +31 more
core   +1 more source

A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals [PDF]

, 2014
This work was supported by a Medical Research Council Partnership grant (G1001787/1) held between the Department of Veterinary Medicine, University of Cambridge (M.A.H.), the School of Clinical Medicine, University of Cambridge (S.J.P.), the Moredun ...
Andrew S. Waller, Boag, A K, Waller, Andrew S., John J. Welch, Sharon J. Peacock, Holden, Matthew T G, Wilson, Katherine, Parkhill, J, Harrison, Ewan M, Holmes, M A, Mark A. Holmes, Waller, Andrew S, Harris, Simon R., Welch, John J., Loeffler, Anette, Harris, Simon R, Boag, Amanda K, Holden, Matthew T. G., Peacock, Sharon J., Lucy A. Weinert, Harris, S R, Anette Loeffler, Morgan, F J E, Holden, M T G, Harrison, E M, Gavin K. Paterson, Paterson, Gavin; id_orcid, Katherine Wilson, Harrison, Ewan M., Ewan M. Harrison, Weinert, Lucy A., Peacock, Sharon J, Paterson, Gavin K., Fiona J. E. Morgan, Weinert, Lucy A, Loeffler, A, Waller, A S, Welch, J J, Simon R. Harris, Peacock, S J, Morgan, Fiona J E, Paterson, G K, Julian Parkhill, Amanda K. Boag, Matthew T. G. Holden, Paterson, Gavin K, Parkhill, Julian, Weinert, L A, Boag, Amanda K., Wilson, K, Welch, John J, Morgan, Fiona J. E., Holmes, Mark A, Holmes, Mark A.   +53 more
core   +2 more sources