Towards an Ontological Representation of Resistance: The Case of MRSa [PDF]
, 2009 This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent ...
Albert Goldfain +2 more
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Prevalence of qacA/B genes and mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) isolates in the setting of chlorhexidine bathing without mupirocin [PDF]
, 2016 OBJECTIVE: We aimed to determine the frequency of qacA/B chlorhexidine tolerance genes and high-level mupirocin resistance among MRSA isolates before and after the introduction of a chlorhexidine (CHG) daily bathing intervention in a surgical intensive ...
Bommarito, Kerry M +7 more
core +2 more sources
Methicillin-resistant staphylococci [PDF]
Journal of Clinical Pathology, 1961 Eighteen strains ofStaph. pyogenes(nine penicillin-sensitive and nine penicillin-destroying) were passaged 40 to 50 times on Celbenin1ditch plates.All strains developed an increase in resistance to Celbenin and eight strains (four penicillin-sensitive and four penicillin-destroying) were able to grow in 100 μg/ml. or more Celbenin.
openaire +3 more sources
Clinical, Microbiological, and Genetic Characteristics of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Bacteremia in a Teaching Hospital [PDF]
, 2014 The emergence of vancomycin intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) is of major concern worldwide. Our objective was to investigate the prevalence, phenotypic and molecular features of hVISA strains isolated from ...
de Gregorio, Stella +9 more
core +1 more source
Methicillin-resistant Staphylococcus aureus [PDF]
Nature Reviews Disease Primers, 2018 Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged, disseminated globally and become a leading cause of bacterial infections in both health-care and community settings. However, there is marked geographical variation in MRSA burden owing to several factors, including differences in local infection control practices and ...
Jan Kluytmans +8 more
openaire +5 more sources
Emerging Multidrug Resistance of Methicillin-Resistant Staphylococcus aureus in Hand Infections. [PDF]
, 2014 BACKGROUND: Methicillin-resistant Staphylococcus aureus has been the most commonly identified pathogen in hand infections at urban centers, but the evolving antibiotic sensitivity profiles of methicillin-resistant Staphylococcus aureus are not known. The
Bender, Samantha +6 more
core +2 more sources
Evidence for the evolutionary steps leading to mecA-mediated ß-lactam resistance in staphylococci [PDF]
, 2017 The epidemiologically most important mechanism of antibiotic resistance in Staphylococcus aureus is associated with mecA–an acquired gene encoding an extra penicillin-binding protein (PBP2a) with low affinity to virtually all β-lactams.
Rolo, J +13 more
core +4 more sources
Methicillin-resistant staphylococci [PDF]
Clinical Microbiology Reviews, 1988 Strains of staphylococci resistant to methicillin were identified immediately after introduction of this drug. Methicillin-resistant strains have unusual properties, the most notable of which is extreme variability in expression of the resistance trait.
openaire +2 more sources
PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance. [PDF]
, 2018 β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Chambers, Henry F +3 more
core +3 more sources
Death associated to methicillin resistant staphylococcus aureus ST8 infection in two dolphins maintained under human care, Italy [PDF]
, 2018 The present study describes the isolation of Methicillin-resistant Staphylococcus aureus (MRSA) from respiratory tract of 2 dolphins of different origin, a stranded juvenile Risso's dolphin (Grampus griseus) and a captive born common bottlenose dolphin ...
Biancani, Barbara +5 more
core +2 more sources