Penicillin dust exposure and penicillin resistance among pharmaceutical workers in Tehran, Iran [PDF]
International Journal of Occupational and Environmental Health, 2016 Background: Antimicrobial resistance (AMR) adversely impacts the prevention and treatment of a wide range of infections and is considered as a serious threat to global public health. Occupational-related AMR is a neglected area of research. Objective: To
Ali Asghar Farshad +2 more
exaly +3 more sources
The effect of MurM and a branched cell wall structure on penicillin resistance in Streptococcus pneumoniae [PDF]
Journal of BacteriologyThe aminoacyltransferase MurM is an important penicillin resistance determinant in Streptococcus pneumoniae. This enzyme attaches a serine or alanine to the side chain of lysine, the third residue of the pentapeptide of lipid II, resulting in branched ...
Ragnhild Sødal Gjennestad +7 more
doaj +2 more sources
Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]
Frontiers in Medicine, 2023 BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi +5 more
doaj +2 more sources
Loss of Pde1 function acts as an evolutionary gateway to penicillin resistance in Streptococcus pneumoniae. [PDF]
Proc Natl Acad Sci U S A, 2023 Streptococcus pneumoniae is a major human pathogen and rising resistance to β-lactam antibiotics, such as penicillin, is a significant threat to global public health.
Kobras CM +8 more
europepmc +2 more sources
Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]
Emerging Infectious Diseases, 2017 Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam +5 more
doaj +2 more sources
Journal of Dairy Science, 2023 : Staphylococcus aureus is a major pathogen in humans and animals. In cattle, it is one of the most important agents of mastitis, causing serious costs in the dairy industry.
I. Ivanovic +6 more
doaj +3 more sources
Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in
mSystems, 2018 Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis +11 more
doaj +4 more sources
A four-year surveillance of β-lactam antibiotic resistance and MRSA in a tertiary hospital in Al-Kharj, Saudi Arabia [PDF]
BMC Infectious DiseasesBackground/objectives Methicillin-resistant Staphylococcus aureus (MRSA) is a major global pathogen and a critical public health concern. Understanding its epidemiology is essential for guiding effective treatment and infection control measures.
Amal Yahya, Alhassan Alrafaie
doaj +2 more sources
Intrinsic Penicillin Resistance in Enterococci
Microbial Drug Resistance, 1996 ABSTRACT Penicillin resistance development in enterococci has been associated with overproduction of a low-affinity penicillin-binding protein (PBP) that is a normal component of the PBP pattern of these bacteria and is apparently able to substitute the functions of the other PBPs. In resistant mutants of
FONTANA, Roberta +3 more
openaire +4 more sources
Emerging Infectious Diseases, 2003 Streptococcus pneumoniae and Neisseria meningitidis have very similar mechanisms of resistance to penicillin G. Although penicillin resistance is now common in S. pneumoniae, it is still rare in N. meningitidis.
L. Temime +3 more
doaj +2 more sources