The effect of MurM and a branched cell wall structure on penicillin resistance in Streptococcus pneumoniae [PDF]
Journal of BacteriologyThe aminoacyltransferase MurM is an important penicillin resistance determinant in Streptococcus pneumoniae. This enzyme attaches a serine or alanine to the side chain of lysine, the third residue of the pentapeptide of lipid II, resulting in branched ...
Ragnhild Sødal Gjennestad +7 more
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Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]
Frontiers in Medicine, 2023 BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi +5 more
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Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]
Emerging Infectious Diseases, 2017 Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam +5 more
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Journal of Dairy Science, 2023 : Staphylococcus aureus is a major pathogen in humans and animals. In cattle, it is one of the most important agents of mastitis, causing serious costs in the dairy industry.
I. Ivanovic +6 more
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Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in
mSystems, 2018 Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis +11 more
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A four-year surveillance of β-lactam antibiotic resistance and MRSA in a tertiary hospital in Al-Kharj, Saudi Arabia [PDF]
BMC Infectious DiseasesBackground/objectives Methicillin-resistant Staphylococcus aureus (MRSA) is a major global pathogen and a critical public health concern. Understanding its epidemiology is essential for guiding effective treatment and infection control measures.
Amal Yahya, Alhassan Alrafaie
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Penicillin-nonsusceptible Streptococcus suis infections in humans: clinical characteristics and antimicrobial synergy testing [PDF]
BMC Infectious DiseasesBackground Antimicrobial resistance in Streptococcus suis represents an increasing global health concern, particularly in Thailand, where human and swine infections remain common and severe.
Wilawan Thipmontree +5 more
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Penicillin dust exposure and penicillin resistance among pharmaceutical workers in Tehran, Iran [PDF]
International Journal of Occupational and Environmental Health, 2016 Roksana Mirkazemi +2 more
exaly +2 more sources
Antibiotics, 2023 For effective case management and chemoprophylaxis of Invasive Meningococcal Disease (IMD), prompt antibiotic treatment is required. N. meningitidis is usually susceptible to antibiotics, but reduced susceptibility to penicillin, ciprofloxacin, and ...
Ioanna Spiliopoulou +3 more
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Restricted Sequence Variation in
mSphere, 2020 A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutation in the penicillin binding protein (PBP) PBP2x. To determine whether this is an isolated case or reflects a broader prevalence of mutations that might ...
Andrew Hayes +4 more
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