Results 21 to 30 of about 318,787 (256)

Clinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study

BMC Infectious Diseases, 2011
Background Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among ...
Gouveia Edilane L, Reis Joice N, Flannery Brendan, Cordeiro Soraia M, Lima Josilene BT, Pinheiro Ricardo M, Salgado Kátia, Mascarenhas Ana, Carvalho M Gloria, Beall Bernard W, Reis Mitermayer G, Ko Albert I   +11 more
doaj   +1 more source

Bacteremic Pneumonia Caused by Penicillin-Resistant Pneumococci: Case Report and Review with a Canadian Perspective

Canadian Journal of Infectious Diseases, 1992
A Canadian adult with bacteremic pneumonia caused by a relatively penicillin-resistant (minimal inhibitory concentration 0.25 μg/mL) Streptococcus pneumoniae is reported, and the published literature regarding penicillin-resistant pneumococci in Canada ...
David R Burdge, Vincent C Woo, Patricia MA Ritchie   +2 more
doaj   +1 more source

Antimicrobial resistance in clinical isolates of Streptococcus pneumoniae in a tertiary hospital in Kuwait, 1997–2007: Implications for empiric therapy

Journal of Infection and Public Health, 2010
Summary: Objective: This study evaluated antibiotic resistance trends in Streptococcus pneumoniae isolated in a tertiary hospital in Kuwait and its implications for empiric therapy.
Molly Johny, Mohammed Babelly, Ina’am Al-Obaid, Kaleefa Al-Benwan, Edet E. Udo   +4 more
doaj   +1 more source

Relationship between Penicillin-Binding Proteins Alterations and β-Lactams Non-Susceptibility of Diseased Pig-Isolated Streptococcus suis

Antibiotics, 2023
Streptococcus suis is a zoonotic pathogen causing disease in both animals and humans, and the emergence of increasingly resistant bacteria to antimicrobial agents has become a significant challenge globally. The objective of this study was to investigate
Kamonwan Lunha, Wiyada Chumpol, Surasak Jiemsup, Sukuma Samngamnim, Pornchalit Assavacheep, Suganya Yongkiettrakul   +5 more
doaj   +1 more source

Increasing penicillin resistance in pneumococci isolated from cerebrospinal fluid samples: Fifteen-year experience from a teaching hospital [PDF]

Journal of Microbiology and Infectious Diseases, 2014
Objective: There have been prominent changes in evaluation of resistance patterns of pneumococci and breakpoint values in recent years. We aimed to investigate the penicillin sensitivity of pneumococcal strains isolated from the ce­rebrospinal fluid ...
Filiz Pehlivanoğlu, Gönül Şengöz, Sevtap Gürsoy   +2 more
doaj   +3 more sources

Penicillin-Binding Proteins in Streptococcus agalactiae and Their Association with Reduced Penicillin Susceptibility: An Overview

Antibiotics
Streptococcus agalactiae are bacteria that can cause a range of infections, some of them life-threatening. Currently, antimicrobial resistance has become a global problem that puts public health at risk.
Leonardo Nagao Ferreira, Bruna Alves Pimentel Hecht, Louisy Sanches dos Santos, Prescilla Emy Nagao   +3 more
doaj   +1 more source

Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae

Journal of Infection in Developing Countries, 2008
Background: Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics ...
Navindra Kumari,1 Parasakthi Navaratnam,2 Shamala Devi Sekaran.1
doaj   +3 more sources

Impact of the revised penicillin susceptibility breakpoints for Streptococcus pneumoniae on antimicrobial resistance rates of meningeal and non-meningeal pneumococcal strains

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: In January 2008, the Clinical Laboratory Standard Institute (CLSI) revised the Streptococcus pneumoniae breakpoints for penicillin to define the susceptibility of meningeal and nonmeningeal isolates.
Badria R. Al-Waili, Sahar Al-Thawadi, Sami Al Hajjar   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source