Results 21 to 30 of about 2,210,070 (253)

An internationally spread clone of Streptococcus pneumoniae evolves from low-level to higher-level penicillin resistance by uptake of penicillin-binding protein gene fragments from nonencapsulated pneumococci. [PDF]

, 2004
Low-level penicillin resistance in an international Streptococcus pneumoniae serotype 19F clone emerging in Switzerland was characterized by mutations in the penicillin-binding protein PBP2x.
Hauser, Christoph, Aebi, Suzanne, Mühlemann, Kathrin   +2 more
core   +1 more source

Penicillin-Binding Proteins in Streptococcus agalactiae and Their Association with Reduced Penicillin Susceptibility: An Overview

Antibiotics
Streptococcus agalactiae are bacteria that can cause a range of infections, some of them life-threatening. Currently, antimicrobial resistance has become a global problem that puts public health at risk.
Leonardo Nagao Ferreira, Bruna Alves Pimentel Hecht, Louisy Sanches dos Santos, Prescilla Emy Nagao   +3 more
doaj   +1 more source

Towards an Ontological Representation of Resistance: The Case of MRSa [PDF]

, 2009
This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent ...
Lindsay G. Cowell, Albert Goldfain, Barry Smith, Lindsay Cowell   +3 more
core   +1 more source

Metal complexes of penicillin and cephalosporin antibiotics [PDF]

, 1975
Includes bibliographical references.The interaction between metal-ions and the penicillin and cephalosporin antibiotics have been studied in an attempt to determine both the site and mechanism of this interaction.
Jackson, Graham Ellis
core   +1 more source

The effect of MurM and a branched cell wall structure on penicillin resistance in Streptococcus pneumoniae

Journal of Bacteriology
The aminoacyltransferase MurM is an important penicillin resistance determinant in Streptococcus pneumoniae. This enzyme attaches a serine or alanine to the side chain of lysine, the third residue of the pentapeptide of lipid II, resulting in branched ...
Ragnhild Sødal Gjennestad, Maria Victoria Heggenhougen, Anja Ruud Winther, Johanne Moldstad, Vegard Eldholm, Morten Kjos, Leiv Sigve Håvarstein, Daniel Straume   +7 more
doaj   +1 more source

Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae

Journal of Infection in Developing Countries, 2008
Background: Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics ...
Navindra Kumari,1 Parasakthi Navaratnam,2 Shamala Devi Sekaran.1
doaj   +3 more sources

Impact of the revised penicillin susceptibility breakpoints for Streptococcus pneumoniae on antimicrobial resistance rates of meningeal and non-meningeal pneumococcal strains

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: In January 2008, the Clinical Laboratory Standard Institute (CLSI) revised the Streptococcus pneumoniae breakpoints for penicillin to define the susceptibility of meningeal and nonmeningeal isolates.
Badria R. Al-Waili, Sahar Al-Thawadi, Sami Al Hajjar   +2 more
doaj   +1 more source

Drug Resistant Streptococcus pneumoniae (DRSP) in the Maltese Islands [PDF]

, 2004
The DRSP prevalence rate for the Maltese Islands was investigated. Consecutive samples were obtained, both from adults and children, from September 2000 through April 2002.
Micallef, Christianne, Cuschieri, Paul, Barbara, Christopher, Cassar, Robert   +3 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States

Emerging Infectious Diseases, 2017
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam, Colin J. Worby, Ryan Gierke, Lesley McGee, Tamara Pilishvili, William P. Hanage   +5 more
doaj   +1 more source