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METHICILLIN RESISTANCE IN STAPHYLOCOCCUS AUREUS
Lancet, The, 1970Abstract Two independent surveys of the frequency of methicillin resistance in Staphylococcus aureus indicate that there was a moderate increase between 1960 and 1963, followed by a stationary period. A second increase began in 1968 and is continuing. Resistant strains have been present in many hospitals for some years, and the more recent increase in
M T Parker, M T Parker
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Methicillin-Resistant Staphylococcus aureus
New England Journal of Medicine, 1989STAPHYLOCOCCUS AUREUS is one of the most versatile human pathogens. In the late 1930s, sulfonamides offered the first challenge to S.
W, Brumfitt, J, Hamilton-Miller
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Expression of resistance to methicillin
Trends in Microbiology, 1994Methicillin-resistant staphylococci have an additional low-affinity penicillin-binding protein, PBP2a (PBP2'), encoded by the mecA gene. The typical heterogeneity seen in the expression of resistance to methicillin and in levels of resistance depends on the concerted action of chromosomally encoded genes, including fem and aux, that are also present in
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Methicillin-Resistant Staphylococcus epidermidis
Southern Medical Journal, 1978Staphylococcus epidermidis is frequently associated with infection of prosthetic heart valves, prosthetic orthopedic devices, and neurosurgical shunts. Penicillinase-resistant semisynthetic penicillins, such as methicillin, have been the therapeutic and prophylactic agents of choice for S epidermidis infection.
W T, Siebert, N, Moreland, T W, Williams
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Methicillin-resistant staphylococcal mastitis
American Journal of Obstetrics and Gynecology, 1989A postpartum patient had a unilateral breast infection that responded to cephalosporin treatment. During therapy, the contralateral breast developed a methicillin-resistant Staphylococcus aureus infection. The patient was hospitalized and treated successfully with intravenous vancomycin.
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Mechanisms of methicillin resistance in staphylococci
APMIS, 1997The continuously high prevalence of methicillin‐resistant staphylococci (MRS) throughout the world is a constant threat to public health, owing to the multiresistant characteristics of these bacteria. Methicillin resistance is phenotypically associated with the presence of the penicillin‐binding protein 2a (PBP2a) not present in susceptible ...
O G, Brakstad, J A, Maeland
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Methicillin-resistant staphylococci
The American Journal of the Medical Sciences, 1972F H, Kayser, T M, Mak
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Methicillin resistant Staphylococcus aureus
Nursing Standard, 1997Methicillin-resistant Staphylococcus aureus (MRSA) has had a major impact on health care causing much anxiety and distress to patients and staff, and resulting in huge financial costs. It has been widely publicised by the media which in some cases has added to people's alarm.
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