Results 231 to 240 of about 126,280 (295)

The Effectiveness of Linezolid and Teicoplanin for Managing Infections After Burn Injuries: A Retrospective Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Gram‐positive infections in burn patients present significant treatment challenges. This study compared the efficacy and safety of linezolid vs. teicoplanin for managing such infections in a clinical setting. Methods We conducted a retrospective study involving 77 burn patients with confirmed Gram‐positive infections at ...
Abolfazl Zendehdel, Maryam Roham, Sanam Soltani, Amirali Jahanshahi, Somayeh Heidarizadi   +4 more
wiley   +1 more source

Ceragenin‐Loaded Tri‐Layered Skin Substitute Composed of Natural and Synthetic Biopolymers for Burn Wound Healing

Journal of Biomedical Materials Research Part A, Volume 114, Issue 6, June 2026.
ABSTRACT Burn wounds present significant clinical challenges due to high infection risk, delayed healing, and extensive tissue damage. The development of biomimetic skin substitutes capable of simultaneously supporting tissue regeneration and preventing infection remains a critical need in burn wound management. In this study, a novel ceragenin (CSA‐44)
Nawal Aljayyousi, Emel Tamahkar Irmak, Esra Karaca, Elif Tümay Özer, Oğuzhan Akgün, Ferda Arı, Aycan Yiğit Çınar, Çağla Bozkurt Güzel, Paul B. Savage, Bilgen Osman   +9 more
wiley   +1 more source

High Versus Low Radiographic Burden Odontogenic Sinusitis: Culture, Histopathology, and Patient‐Reported Outcomes

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
This study investigated clinical, histopathologic, and symptomatic differences between odontogenic sinusitis patients with high versus low radiographic burden. High radiographic burden disease was associated with older age and increased tissue inflammation, while significant postoperative symptom improvement was only observed in the high‐burden cohort.
Landon E. Ebbert, Nitish Kumar, Devyani Lal, Amar Miglani, Michael J. Marino   +4 more
wiley   +1 more source

Kefir: A Potential Gut Microbiota Modulator: A Systematic Review of Human Interventional Studies

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Daily cow's milk kefir intake transiently enriches gut microbiota, modulates the intestinal environment by increasing SCFA and reducing pH and oxygen, and exerts antimicrobial effects via SCFAs, bacteriocins, exopolysaccharides, and microbial fractions, highlighting its potential for gut health promotion.
Mohammed Hamsho, Yazan Ranneh, Batoul Kaddour, Sundus Alfakhri, Hale Hacıbayram, Wijdan Shkorfu, Merve Terzi, Abdulmannan Fadel   +7 more
wiley   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Production of Multiple Variants of the Antimicrobial Sactipeptide Gnavucin D by the Human Gut Isolate Mediterraneibacter gnavus HB038

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gnavucin D, a novel antibacterial sactipeptide produced by Mediterraneibacter gnavus HB038, exhibits activity against multiple pathogens, including Clostridium perfringens, Streptococcus agalactiae, Bacillus cereus, and vancomycin‐resistant Enterococcus.
Mengfan Ding, Felipe Miceli de Farias, Paula M. O'Connor, Xiaohui Huang, Fiona C. Ross, Elaine C. Kennedy, Colin P. Hawkes, Colin Hill, Catherine Stanton, Reynolds Paul Ross   +9 more
wiley   +1 more source

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair, Syeda Zaira Batool, Mohamed H. Helal, Naila Afghan   +3 more
wiley   +1 more source

Wastewater‐Based Assessment of Antimicrobial Resistance and Bacterial Communities in Urban and Rural Areas in the Province of Trento (Italy)

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Wastewater from urban and rural areas was analyzed to investigate antimicrobial‐resistant bacteria and resistance genes. ESBL‐Escherichia coli and genes coding for clinically relevant resistances, namely, those to macrolides, carbapenems, and vancomycin, were higher in urban than in rural areas.
Maya Petricciuolo, Agnese Carnevali, Alessia Torboli, Mattia Postinghel, Alessia Guasticchi, Paola Foladori, Maria Cadonna, Ermanno Federici   +7 more
wiley   +1 more source

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith, Rehana Bagodiya, Phuong Luong, Sakshi Shinde, Christopher M. Bland, Christopher Barry, Michael G. Bartlett, Nicholas R. Fox, Trisha N. Branan   +8 more
wiley   +1 more source