Results 151 to 160 of about 180,890 (291)

No Increased Risk of Infection Following a Protocol Change to Decrease Duration of Perioperative Antibiotic Prophylaxis in Liver Transplantation

Transplant Infectious Disease, EarlyView.
There was no increased rate of surgical site infection or bacteremia in liver transplant recipients following a decrease in perioperative antibiotic prophylaxis duration, with a change from 2.4% to 2.8% in patients hospitalized prior to transplant and 7.5% to 2.9% in other patients.
Hutton Brandon, Crystal M. Truax, Eduardo Rodriguez Zarate, Brandon J. Tritle, Hannah Imlay   +4 more
wiley   +1 more source

Impact of Advanced Age on Posttransplant Infections and Outcomes in Solid Organ Transplant Recipients: A Multicenter Cohort Study

Transplant Infectious Disease, EarlyView.
Advanced age (≥60 years) was independently associated with higher mortality in solid organ transplant recipients, despite similar infection incidence. Even a single infection episode significantly increased mortality risk, underscoring the need for close clinical monitoring in elderly patients.
Sibel Altunisik Toplu, Vildan Avkan Oguz, Esra Tanyel, Imran Hasanoglu, Bengu Tatar, Tuba Turunc, Gule Cinar, Yesim Uygun Kizmaz, Gulnur Kul, Adem Kose, Muammer Celik, Adam Uslu, Ebru Oruc, Ezgi Erdal Karakas, Nilay Danis, Yelda Deligoz Bildaci, Sezai Yilmaz, Yasar Bayindir, Hande Arslan   +18 more
wiley   +1 more source

Stimuli‐Responsive Crosslinked Chitosan/PVP/PEG Hydrogel Networks for Targeted Drug Delivery and Antimicrobial Performance

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT In this study, a unique pH‐sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to deliver different drugs with distinct release profiles, including diclofenac sodium and ciprofloxacin, and ...
Danial Mazhar, Sumra Afzal, Safia Hassan, Zahid Imran, Shabana Mehreen   +4 more
wiley   +1 more source

Toddlers and terriers: a One Health partnership to combat antimicrobial resistance

Journal of Small Animal Practice, EarlyView.
M. Prodanuk, F. Emdin
wiley   +1 more source

Kefir: A Potential Gut Microbiota Modulator: A Systematic Review of Human Interventional Studies

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Daily cow's milk kefir intake transiently enriches gut microbiota, modulates the intestinal environment by increasing SCFA and reducing pH and oxygen, and exerts antimicrobial effects via SCFAs, bacteriocins, exopolysaccharides, and microbial fractions, highlighting its potential for gut health promotion.
Mohammed Hamsho, Yazan Ranneh, Batoul Kaddour, Sundus Alfakhri, Hale Hacıbayram, Wijdan Shkorfu, Merve Terzi, Abdulmannan Fadel   +7 more
wiley   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Genome co-adaptation and the evolution of methicillin resistant Staphylococcus aureus. [PDF]

Genome Biol
Ko S, Cummins EA, Monteith W, Sheppard SK.   +3 more
europepmc   +1 more source

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith, Rehana Bagodiya, Phuong Luong, Sakshi Shinde, Christopher M. Bland, Christopher Barry, Michael G. Bartlett, Nicholas R. Fox, Trisha N. Branan   +8 more
wiley   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon, Xianjin Qin, Marjon Zamani, Ariel L. Furst, Cassandra E. Callmann   +4 more
wiley   +2 more sources