Crystals, 2020 The spontaneous S-alkylation of the thyreostatic drug methimazole (1-methyl-1,3-dihydro-1H-imidazole-2-thione, 1) with 1,2-dichloroethane at room temperature, in dark or light conditions, led to the formation of its related substance 1,2-bis[(1-methyl-1H-
Leo Štefan +3 more
doaj +1 more source
Projected reduction in healthcare costs in Belgium after optimization of iodine intake : impact on costs related to thyroid nodular disease [PDF]
, 2010 Background: Several surveys in the last 50 years have repeatedly indicated that Belgium is affected by mild iodine deficiency. Within the framework of the national food and health plan in Belgium, a selective, progressive, and monitored strategy was ...
Annemans, Lieven +4 more
core +1 more source
Hyperthyroid Hypokalemic Periodic Paralysis in a Nepali Male; A Case Report
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT Hyperthyroid Hypokalemic Periodic Paralysis (HHPP), marked by acute weakness and hypokalemia. Prompt potassium replacement and hyperthyroidism management are essential to prevent life‐threatening outcomes. This case highlights its presentation in a Nepali male, reinforcing the need for high clinical suspicion.
Ashish Tamang +6 more
wiley +1 more source
Double Filtration Plasmapheresis for Thyroid Storm With Encephalopathy: A Case Report
Journal of Clinical Apheresis, Volume 40, Issue 5, October 2025.ABSTRACT Thyroid storm is a life‐threatening endocrine emergency with a mortality rate of up to 17%. Standard treatment includes antithyroid drugs (ATD), β‐blockers, and glucocorticoids. However, some patients may require blood purification therapies, such as plasmapheresis, due to the ineffectiveness of standard treatments or contraindications like ...
Qisheng Lin +5 more
wiley +1 more source
Sepsis-induced Pancytopenia in an Adolescent Girl with Thyroid Storm: A Case Report
JCRPEThyroid storm is a rare but life-threatening condition mainly triggered by infection and abrupt discontinuation of antithyroid drug therapy for Graves’ disease. Pancytopenia is a rare adverse reaction to antithyroid drugs.
Qing Zhou +4 more
doaj +1 more source
Structural mechanism for bacterial oxidation of oceanic trimethylamine into trimethylamine N -oxide [PDF]
, 2017 Trimethylamine (TMA) and trimethylamine N-oxide (TMAO) are widespread in the ocean and are important nitrogen source for bacteria. TMA monooxygenase (Tmm), a bacterial flavin-containing monooxygenase (FMO), is found widespread in marine bacteria and is ...
Chen, Xiu-Lan +16 more
core +1 more source
Journal of Evaluation in Clinical Practice, Volume 31, Issue 7, October 2025.ABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
N. N. Ngcobo
wiley +1 more source
Application of Agents Against Interferon-Gamma-Dependent Chemokines in Immunotherapy [PDF]
, 2015 The CXC chemokine receptor (CXCR) 3 and its chemokines (CXCL9, CXCL10, CXCL11) are involved in the pathogenesis of autoimmune disesases. Under the influence of interferon (IFN) γ, the IFNγ-inducible chemokines are secreted by lymphocytes, and by ...
Antonelli, Alessandro +4 more
core +1 more source
Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats [PDF]
, 2016 BACKGROUND: Hypertension is a common problem in elderly cats. In most cats, systolic blood pressure (SBP) of
Bijsmans, E S +5 more
core +2 more sources
(E)-2-[(2,3-Dibromoallyl)sulfanyl]-1-methyl-1H-imidazol-3-ium bromide
IUCrData, 2016 The title salt, C7H9Br2N2S+·Br−, was obtained from methimazole (1-methyl-3H-imidazole-2-thione) by S-allylation using 1,2,3-tribromopropene. A positional disorder of the bromine atoms at the allyl chain was observed, with each Br atom equally disordered ...
Stefan Oberparleiter +3 more
doaj +1 more source