Results 41 to 50 of about 67,731 (192)
Nicotine Effects and the Endogenous Opioid System
Journal of Pharmacological Sciences, 2014 .: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins,
Shiroh Kishioka +3 more
doaj +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
, 1997 IntroductionT:h e aim of this study was to investigate the effect of anti-methionine- enkephalin antibodies on local inflammatory reaction. Materialsa nd Methods: Eight-weeks old male Wistar rats were used in experiments.
Vujić-Redžić, Vesna +5 more
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Backbone Protecting Groups for Enhanced Peptide and Protein Synthesis
Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.This review provides a comprehensive account of the use of backbone N‐protecting groups in peptide synthesis. It includes detailed synthetic methods relating to their introduction and removal and their application to “difficult” peptides and proteins of biological significance in both academic and industry contexts.
Samuel J. Paravizzini +3 more
wiley +2 more sources
The FEBS Journal, Volume 293, Issue 9, Page 2772-2793, May 2026.The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima +12 more
wiley +1 more source
, 1979 A hexapeptide that we have named pro-methionine-enkephalin has been isolated from acid extracts of porcine hypothalami and found to have the amino acid sequence H-Tyr-Gly-Gly-Phe-Met(O)-Arg-OH.
Coy, David H +4 more
core +1 more source
Effects of Electroacupuncture at Different Time on Brain Methionine-Enkephalin Contents in Rats
针刺研究, 1995 The basic level of methionine-enkephalin (MEK) in rat medulla oblongata plus Pons was thehighest at 05: 00 o'clock and the lowest at 23: 00. In both the hypothalamus and the striatum at 05: 00 MEK levles were respectively higher.than those at 11: 00, 17:
王友京, 王双坤
doaj +2 more sources
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2876-2890, May 2026.ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng +14 more
wiley +1 more source
Mass Spectrometry Reviews, Volume 45, Issue 2, Page 218-230, March/April 2026.ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
, 1976 The natural opiate methionine-enkephalin and its D-alanine 2 analog were iodinated by a method involving lactoperoxidase and purified by partition chromatography on Sephadex G-25.
Coy, David H +3 more
core +1 more source