Results 31 to 40 of about 67,731 (192)

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source

Venom‐Derived Bioactive Peptides: From Toxins to Therapeutics

Advanced Therapeutics, Volume 9, Issue 8, August 2026.
Venomics → Target Identification → Peptide Optimization → Therapeutic Translation Bioactive venom peptides targeting ion channels, enzymes, and receptors drive the development of next‐generation precision therapeutics. ABSTRACT Venoms are complex biochemical mixtures composed of diverse bioactive components, including proteins, enzymes, small molecules,
Eldho Sabu, Othman Al Musaimi
wiley   +1 more source

Neuropharmacological actions of enkephalin after systemic administration

, 1976
A pentapeptide, methionine-enkephalin, which interacts with opiate receptors in the brain, was found to markedly potentiate the behavioral effects of DOPA when administered intraperitoneally into mice.
Coy, David H, Kastin, Abba J, Schally, Andrew V, Spirtes, Morris A, Plotnikoff, Nicholas P, Christensen, Carl W   +5 more
core   +1 more source

Proteome‐Wide Prediction of Putative Bemisia tabaci Effector Candidates and Transient Validation of BtApe‐Mediated Suppression of Tomato Immune Responses

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 3, July 2026.
The workflow illustrates the process of identifying and preliminarily validating the functionality of effectors in Bemisia tabaci. The proteome of B. tabaci served as the initial input for a multiparameter effector prediction pipeline, which integrates secretory features, subcellular targeting predictions, and parallel computational tools to generate a
Prakash Kolanchi, Murugan Marimuthu, Mohana Pradeep Rangaraj Kumar, Vamsi Nalam, Punya Nachappa   +4 more
wiley   +1 more source

Methionine enkephalin, substance P, and homovanillic acid in the CSF of parkinsonian patients

, 1984
Methionine-enkephalin, substance P, and homovanillic acid concentrations were measured in the CSF of subjects not affected by neurologic disorders (group 1), and in parkinsonian patients who had a slight or moderate (group 2) or severe (group 3 ...
G. Pezzoli, A. E. Panerai, A. Longo, D. Passerini, A. Carenzi, A. Di Giulio   +5 more
core   +1 more source

Synthesis and opioid activities of stereoisomers and other D-amino acid analogs of methionine-enkephalin

, 1976
A series of D-amino acid-substituted analogs of the opiate peptide, methionine 5-enkephalin, were synthesized by solid-phase methods and tested for their abilities to inhibit electrically-evoked contractions of mouse vasa deferentia and to compete with ...
Fertel, R, Walker, J.M, Berntson, G.G, Labrie, F, Morin, O, Schally, A.V, Caron, N.G, Sandman, C.A, Kastin, A.J, Coy, D.H   +9 more
core   +1 more source

Anti-methionine-enkephalin antibodies decrease local inflammatory reaction

, 1997
Introduction: Methionine-enkephalin ix an opioid peptide which exerts immunomodulatory activity after central and peripheral ' application. The aim of this study was to investigate the effects of anti-Methionine-enkephalin antibodies on local ...
Vujić-Redžić, Vesna, Stanojević, Stanislava, Radulović, Jelena, Kovačević-Jovanović, Vesna, Dimitrijević, Mirjana, Miletić, Tatjana   +5 more
core   +1 more source

Sensory Neuropeptides and Endogenous Opioids Expression in Human Dental Pulp with Asymptomatic Inflammation: In Vivo Study

Mediators of Inflammation, 2015
Purpose. This study quantified the expression of substance P (SP), calcitonin gene-related peptide (CGRP), β-endorphins (β-End), and methionine-enkephalin (Met-Enk) in human dental pulp following orthodontic intrusion. Methods.
Daniel Chavarria-Bolaños, Hector Flores-Reyes, Nelson Lombana-Sanchez, Bernardino Cerda-Cristerna, Amaury Pozos-Guillen   +4 more
doaj   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Patterns of enkephalin immunolabeling in the pulmonate snail Cepea nemoralis and related molluscs.

, 1993
In the land pulmonate snailCepaea nemoralis, immunocytochemical localization of methionine- and leucine-enkephalin-like substances was demonstrated in specific populations of brain neurons.
Sakharov, Dmitri A, Nezlin, Leonid,, Elofsson, Rolf, Sakharov, Dmitri A,, Moroz, Leonid, Nezlin, Leonid, Elofsson, Rolf,   +6 more
core   +1 more source