Results 11 to 20 of about 67,731 (192)

Methionine enkephalin: immunomodulator in normal volunteers, cancer and AIDS patients [PDF]

Memorias do Instituto Oswaldo Cruz, 1987
Clinical studies of the immunological effects of methionine enkephalin in normal volunteers, cancer, and AIDS patients are summarized. The major immunology changes seen were increases in T cell subsets, natural killer activity, as well as mitogen ...
Nicholas P. Plotnikoff, Gerald C. Miller, Nadim F. Nimeh, Joseph Wybran   +3 more
doaj   +2 more sources

The influence of the methionine residue on the dissociation mechanisms of photoionized methionine-enkephalin probed by VUV action spectroscopy [PDF]

, 2021
VUV action spectroscopy has recently gained interest for the study of peptides and proteins. However, numerous aspects of the fundamental processes involved in the photodissociation are yet to be understood.
Schlathölter, Thomas, Schwob, L., Pieterse, C.L., Pieterse, Cornelius, Schlathölter, Thomas; id_orcid, Dörner, S., Girod, M., Girod, Marion, Pieterse, Cornelius L., Schwob, Lucas, Techert, S., Techert, Simone, Bari, S., Pieterse, Cornelius Louwrens, Schlathölter, T., Bari, Sadia, Schlathoelter, Thomas, Schubert, Kaja, Schubert, K., Dörner, Simon, MacAleese, L., MacAleese, Luke, Bari, Sadia; Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany, Pieterse, Cornelius L.; National Physical Laboratory, Teddington, UK, Girod, Marion; Univ Lyon, Université Claude Bernard Lyon 1, Institut des Sciences Analytiques, CNRS UMR 5280, Villeurbanne, France, Techert, Simone; Institut für Röntgenphysik, Georg-August Universität Göttingen, Göttingen, Germany, Schubert, Kaja; Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany, Dörner, Simon; Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany, Schlathölter, Thomas; Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands, MacAleese, Luke; Univ Lyon, Université Claude Bernard Lyon 1, Institut Lumière Matière, CNRS UMR 5306, Lyon, France, Schwob, Lucas; Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany, Cornelius L. Pieterse, Thomas Schlathölter, Simon Dörner, Marion Girod, Simone Techert, Luke MacAleese, Sadia Bari, Lucas Schwob, Kaja Schubert   +39 more
core   +2 more sources

Probing the Influence of Sulfur-Aromatic Interactions on the Electronic Structure of Gas-Phase Peptides. [PDF]

Chemistry
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Pille L, Ortiz-Mahecha C, Oostenrijk B, Leroux J, Girod M, Hirsch K, MacAleese L, Meißner RH, Scuderi D, Unger I, Zamudio-Bayer V, Bari S, Schwob L.   +12 more
europepmc   +2 more sources

THE DISTRIBUTION OF METHIONINE‐ENKEPHALIN AND LEUCINE‐ENKEPHALIN IN THE BRAIN AND PERIPHERAL TISSUES [PDF]

British Journal of Pharmacology, 1977
A method is described for the rapid extraction of opioid peptides from the brain and other tissues. The method is based on acid extraction of tissues followed by adsorption of the extract onto Amberlite XAD‐2 resin. Elution with methanol separates the enkephalins and α‐endorphin from β‐endorphin.Over 90% of the opioid peptide activity isolated from ...
J, Hughes, H W, Kosterlitz, T W, Smith
openaire   +5 more sources

‘Acetaldehyde‐enkephalins’: elucidation of the structure of the acetaldehyde adducts of methionine‐enkephalin and leucine‐enkephalin [PDF]

FEBS Letters, 1980
The two major endogenous opioid pentapeptides, methionine-enkephalin and leucine-enkephalin [ 1,2] rapidly react with acetaldehyde, under very mild conditions, to give an ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin [Met’] and ‘acetaldehyde-enkephalin [Leu”], respectively 231.
Summers, Michael C., Gidley, Michael J., Sanders, Jeremy K.   +2 more
openaire   +5 more sources

Computational Approach for Protein Structure Prediction [PDF]

Healthcare Informatics Research, 2013
ObjectivesTo predict the structure of protein, which dictates the function it performs, a newly designed algorithm is developed which blends the concept of self-organization and the genetic algorithm.MethodsAmong many other approaches, genetic algorithm ...
Amouda Venkatesan, Jeyakodi Gopal, Manimozhi Candavelou, Sowjanya Gollapalli, Kayathri Karthikeyan   +4 more
doaj   +1 more source

Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis

Annals of Hepatology, 2008
Endogenous opioids participate in growth regulation. Liver regeneration relates to growth. Thus, we explored the expression of methionine enkephalin and of the delta opioid receptor 1 immunoreactivities with a polyclonal rabbit antibody in deparaffinized
Vijaya D. Boyella, Anthony D. Nicastri, Nora V. Bergasa   +2 more
doaj   +1 more source

Functional Characterization and Molecular Marker Development of the Proenkephalin as Biomarker of Food Addiction in Food Habit Domestication of Mandarin Fish (Siniperca chuatsi)

Fishes, 2022
Proenkephalin (PENK), as the precursor of endogenous opioid enkephalin (ENK), is widely present in the nervous system and plays an important role in animal food addiction and rewarding behavior.
Yingcen Li, Yunliang Miao, Xufang Liang, Shan He   +3 more
doaj   +1 more source

A close neuroanatomical relationship between the enkephalinergic (methionine-enkephalin) and tachykininergic (substance P) systems in the alpaca diencephalon

Folia Histochemica et Cytobiologica, 2020
INTRODUCTION: In the alpaca diencephalon, the distribution of immunoreactive cell bodies and fibers containing methionine-enkephalin (MET) or substance P (SP) has been studied. MATERIAL AND METHODS: The immunohistochemical study was performed by standard
Pablo Sánchez, Manuel Lisardo Sánchez, Arturo Mangas, Luís Ángel Aguilar, Rafael Coveñas   +4 more
doaj   +1 more source

Methionine-Enkephalin in Bone and Joint Tissues [PDF]

Journal of Bone and Mineral Research, 1998
Abstract Methionine-enkephalin (met-enk), an endogenous opiate, mimics many of the effects of morphine by binding to opiate receptors, thereby eliciting similar cellular and behavioral effects. Using biochemical and immunohistochemical techniques, several peptides have been identified in bone and joint tissues.
A M, Elhassan, J U, Lindgren, K, Hultenby, J, Bergstrom, A, Adem   +4 more
openaire   +2 more sources