Results 21 to 30 of about 67,731 (192)

Stabilization and Reactions of Sulfur Radical Cations: Relevance to One-Electron Oxidation of Methionine in Peptides and Proteins

open access: yesCHIMIA, 2008
Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski   +2 more
doaj   +1 more source

Methionine-enkephalin-treatment suppresses the pituitary-ovary axis in the cichlid fish Oreochromis mossambicus

open access: yesAquaculture Reports, 2020
The involvement of endogenous opioid peptides in regulation of reproductive activity is implicated in a majority of vertebrates. Methionine-enkephalin (M-ENK) is an endogenous opioid peptide neurotransmitter produced in the central nervous system ...
C.B. Ganesh, Vijayalaxmi
doaj   +1 more source

Maturation of Circulatory Responses to Methionine-Enkephalin [PDF]

open access: yesPediatric Research, 1983
The cardiovascular and respiratory effects of the naturally occurring endogenous opiate, methionine-enkephalin, were studied in 23 fetal sheep, five newborn lambs, 15 pregnant sheep, and four nonpregnant ewes. The opiate peptide produced dose-dependent decreases in heart rate and blood pressure in fetal and neonatal lambs but increased heart rate and ...
E F, Lagamma, J, Itskovitz, A M, Rudolph
openaire   +2 more sources

Targeted Cell Reprogramming Produces Analgesic Chromaffin-Like Cells from Human Mesenchymal Stem Cells

open access: yesCell Transplantation, 2013
Transplantation of allogeneic adrenal chromaffin cells demonstrated the promise of favorable outcomes for pain relief in patients. However, there is a very limited availability of suitable human adrenal gland tissues, genetically well-matched donors in ...
T. Qu M.D., Ph.D.   +5 more
doaj   +1 more source

Opioid mediated activity and expression of mu and delta opioid receptors in isolated human term non-laboring myometrium [PDF]

open access: yes, 2013
The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been shown to alter spontaneous ...
McMorrow, Jason P.   +10 more
core   +1 more source

Genetically Engineered Human Mesenchymal Stem Cells Produce Met-Enkephalin at Augmented Higher Levels in Vitro

open access: yesCell Transplantation, 2006
We have reported that transplantation of adrenal medullary chromaffin cells that release endogenous opioid peptides into pain modulatory regions in the CNS produce significant antinociceptive effects in patients with terminal cancer pain.
Ikuko Sugaya   +3 more
doaj   +1 more source

Acetaldehyde‐enkephalins: pronounced changes in the opiate activity of methionine‐enkephalin and leucine‐enkephalin on reaction with acetaldehyde [PDF]

open access: yesFEBS Letters, 1980
We have shown that the two major endogenous opioid peptides, methionine-enkephalin and leucineenkephalin [ 1,2] (enkephalin [Met’] and enkephalin[Leu’]) rapidly react with acetaldehyde in aqueous buffers to give a stable ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin[Met’]’ and ‘acetaldehyde-enkephalin [Leu’]‘, respectively ...
Summers, Michael C., Hayes, Roger J.
openaire   +2 more sources

An investigation of the effects of methionine-enkephalin and cocaine on the immune system.

open access: yes, 1993
An investigation of the effects of methionine-enkephalin and cocaine on the immune ...
Chao. Chen (7956656)
core   +2 more sources

Biomimetic Chemistry on Tandem Protein/Lipid Damages under Reductive Radical Stress

open access: yesCHIMIA, 2008
The study of radical stress in the biological environment needs a comprehensive vision of all possible reactive species and their mechanisms. Among them, reductive stress is evaluated for its selective target of sulfur-containing compounds.
Sílvia Atrian   +8 more
doaj   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin   +6 more
wiley   +1 more source

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