Results 91 to 100 of about 104,357 (299)

Subdifferentials and Stability Analysis of Feasible Set and Pareto Front Mappings in Linear Multiobjective Optimization [PDF]

, 2020
The paper concerns multiobjective linear optimization problems in Rn that are parameterized with respect to the right-hand side perturbations of inequality constraints.
Cánovas Cánovas, María Josefa, López Cerdá, Marco A., Mordukhovich, Boris S., Parra López, Juan   +3 more
core   +1 more source

A Component-level Resistance Characteristic Prediction Method for Marine Gas Turbine Intake Systems Based on a Neural Network Model [PDF]

Journal of Applied Fluid Mechanics
In order to improve the accuracy and efficiency of resistance characteristic prediction of marine gas turbine intake system, a resistance characteristic prediction method based on component-level numerical simulation and neural network model is proposed ...
J. Dai, Z. Xu, Y. Yuan, Y. He, R. Wang, J. Zhu, Z. Wang   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

AN INTERIOR-POINT METHOD FOR MPECs BASED ON STRICTLY FEASIBLE RELAXATIONS. [PDF]

An interior-point method for solving mathematical programs with equilibrium constraints (MPECs) is proposed. At each iteration of the algorithm, a single primaldual step is computed from each subproblem of a sequence.
Michael P. Friedlander, Francisco J. Nogales, Angel Víctor de Miguel, Stefan Scholtes   +3 more
core  

An interior point method for linearly constrained multiobjective optimization based on suitable descent directions [PDF]

, 2009
The aim of this paper is the development of an algorithm to find the critical points of a linearly constrained multiobjective optimization problem. The proposed algorithm is an interior point method based on suitable directions that play the role of ...
MOLHO, ELENA, Miglierina Enrico, Recchioni Maria Cristina, Recchioni M. C., Miglierina, Enrico   +4 more
core  

Gliding Footprint Calculation Method for Aircraft with Thrust Failure Based on Six-Degree-of-Freedom Flight Envelope and Back-Propagation Artificial Neural Network

Aerospace
In hostile environments, engine damage is of particular concern since the engine is the only component to generate thrust that affects survivability.
Zhiwei Chen, Yuxue Ge, Jie Yuan, Yang Pei   +3 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Face Recognition using Similarity Pattern of Image Directional Edge Response

Advances in Electrical and Computer Engineering, 2014
An effective face descriptor is critical for a successful face recognition system and must overcome the challenges of changing environment. The face representation must have discriminatory information and be computationally feasible for any face ...
BASHAR, F., KHAN, A., AHMED, F., KABIR, H.   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source