Results 71 to 80 of about 694,961 (287)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Face Recognition using Similarity Pattern of Image Directional Edge Response
Advances in Electrical and Computer Engineering, 2014 An effective face descriptor is critical for a successful face recognition system and must overcome the challenges of changing environment. The face representation must have discriminatory information and be computationally feasible for any face ...
BASHAR, F. +3 more
doaj +1 more source
Edges vs Circuits: a Hierarchy of Diameters in Polyhedra [PDF]
, 2014 The study of the graph diameter of polytopes is a classical open problem in polyhedral geometry and the theory of linear optimization. In this paper we continue the investigation initiated in [4] by introducing a vast hierarchy of generalizations to the ...
Borgwardt, Steffen +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Box-constrained vector optimization: a steepest descent method without “a priori” scalarization [PDF]
In this paper a notion of descent direction for a vector function defined on a box is introduced. This concept is based on an appropriate convex combination of the “projected” gradients of the components of the objective functions.
Miglierina Enrico +2 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Stress-Sensitivity-Based Process Optimization Method for Machining Thin-Walled Parts
LubricantsThin-walled partition frame parts are key load-bearing components in aerospace structures. Machining deformation directly affects assembly accuracy and service reliability.
Haili Jia +4 more
doaj +1 more source
Evaluating and combining digital video shot boundary detection algorithms [PDF]
, 2000 The development of standards for video encoding coupled with the increased power of computing mean that content-based manipulation of digital video information is now feasible.
Berrut, Catherine +5 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A survey of methods of feasible directions for the solution of optimal control problems [PDF]
Three methods of feasible directions for optimal control are reviewed. These methods are an extension of the Frank-Wolfe method, a dual method devised by Pironneau and Polack, and a Zontendijk method. The categories of continuous optimal control problems
Polak, E.
core +1 more source