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YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source
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Cross-Validation Methods

Journal of Mathematical Psychology, 2000
This paper gives a review of cross-validation methods. The original applications in multiple linear regression are considered first. It is shown how predictive accuracy depends on sample size and the number of predictor variables. Both two-sample and single-sample cross-validation indices are investigated. The application of cross-validation methods to
openaire   +3 more sources

Methods validation: AOAC’s three validation systems

Accreditation and Quality Assurance, 1998
Validated methods of analysis are needed for many purposes: enforcement of regulations, import/export control, in accredited laboratories, academia, institutions. The AOAC INTERNATIONAL Official Methods Program is designed to provide fully validated methods of analysis, based on interlaboratory testing by a minimum of eight laboratories.
openaire   +1 more source

Validation of new methods

Forensic Science International, 2007
Reliable analytical data are a prerequisite for correct interpretation of toxicological findings in the evaluation of scientific studies, as well as in daily routine work. Unreliable analytical data might not only be contested in court, but could also lead to unjustified legal consequences for the defendant or to wrong treatment of the patient ...
Frank T, Peters   +2 more
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Validation of Bioanalytical Methods

Pharmaceutical Research, 1991
Validation of bioanalytical methods used to generate data for pharmacokinetic and bioavailability studies is approached by a variety of techniques and is subject to many different methods of interpretation. This Review puts the various techniques into perspective and discusses pitfalls which may occur in interpretation of validation data.
H T, Karnes, G, Shiu, V P, Shah
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Practical method validation: Validation sufficient for an analysis method

Mikrochimica Acta, 1998
Validation of an analysis method depends on the purpose of the method, the chosen technique and the procedure in question. Methods are used for different research, product development, process control and quality control purposes. The human and economical importance of results vary. Each of the techniques used, such as chromatography-(HPLC, HRGC, TLC),
P. Bruce, P. Minkkinen, M. -L. Riekkola
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Validation of Computational Methods

2016
In this chapter, we provide an overview of how (Quantitative) Structure Activity Relationships, (Q)SARs, are validated and applied for regulatory purposes. We outline how chemical categories are derived to facilitate endpoint specific read-across using tools such as the OECD QSAR Toolbox and discuss some of the current difficulties in addressing the ...
Grace, Patlewicz   +2 more
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