Results 61 to 70 of about 8,745,280 (351)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Evolution of urban planning law in light of the legal positions of the Constitutional Court of the Russian Federation

open access: yesЮридический вестник Самарского университета
Using the example of urban planning law as a codified branch of law with a formally uncertain status, the article reveals the importance of constitutionalism for the purposes of creating such certainty.
N. A. Vovk
doaj   +1 more source

The Methodology of Mathematics [PDF]

open access: yesThe Mathematical Gazette, 1995
This essay is based on a talk given by the first author to students and staff of the Departmento de Geometria e Topologia at the University of Seville in November 1993. The issues presented there have been part of a continued debate and discussion at Bangor over many years, and this explains why this is a joint paper.
Brown, Ronald, Porter, Timothy
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Statistical Policy Working Paper 11. A Review of Industry Coding Systems [PDF]

open access: yes
The Working Group on Industry Coding was initiated by the Administrative Records Subcommittee of the Federal Committee on Statistical Methodology to review the various existing industry coding systems and study their relationships, comparability and ...
United States. Federal Committee on Statistical Methodology
core   +1 more source

Guide méthodologique pour l'analyse spatiale du covid-19 dans les zones urbaines non métropolitaines du Brésil

open access: yesConfins
This article presents a methodological guide for analyzing COVID-19 at the intra-urban scale in non-metropolitan areas of south-central Brazil. To this end, it briefly discusses the COVID-19 pandemic and pertinent questions for making COVID-19 maps in ...
João Pedro Pereira Caetano de Lima   +1 more
doaj   +1 more source

Occurrence of depression in patients with psoriasis – the role of inflammation, stress and mechanism of the vicious circle

open access: yesJournal of Pre-Clinical and Clinical Research, 2020
Introduction Psoriasis is a chronic skin disease which can have a detrimental impact on the patient’s life. The correlation between depression, psoriasis and inflammation is a subject of many publications. The depressive and psoriatic symptoms, unhealthy
Aleksandra Amalia Kuchnicka   +4 more
doaj   +1 more source

The methodology of the artificial [PDF]

open access: yesBehavioral and Brain Sciences, 2001
Biorobotics research should not only target “realistic” models of living systems and be judged exclusively from that perspective. It should pay just as much attention to formal models and artificial systems. They allow the examination of assumptions which do not necessarily hold for living systems, but precisely therein lies their value.
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The correllation between incidence rate of pertussis and vaccination rate of children from 1998 to 2016 in Poland

open access: yesJournal of Education, Health and Sport, 2019
Introduction and purpose: Pertussis is becoming a more and more common problem among polish children and youth. In the group of newborns and infants the pertussis course can be severe and lead to serious complications even including death from the ...
Jakub Czarnota   +5 more
doaj   +3 more sources

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