Results 71 to 80 of about 8,745,280 (351)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Methodologies with Objects-Methodological Objections

open access: yes, 2020
This paper attempts to contribute to the feminist discussion on the politics of matter, giving account of methodological proposals to research with objects and of how they interfere in our research. In this methodological meta-reflection we put to dialogue two studies about the role of objects in social life, by following two entries: (1) the review of
Callén Moreu, Blanca   +1 more
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Logic, methodology, and philosophy of science VI : proceedings of the Sixth International Congress of Logic, Methodology, and Philosophy of Science, Hannover, 1979 /

open access: yes, 1982
Logic, Methodology and Philosophy of Science VI.Includes bibliographical references and index.Electronic reproduction.Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version
Cohen, L. Jonathan(Laurence Jonathan)   +1 more
core  

Tools to assess the measurement properties of quality of life instruments: a meta-review

open access: yesBMJ Open, 2020
Objective This meta-review aims to discuss the methodological, research and practical applications of tools that assess the measurement properties of instruments evaluating health-related quality of life (HRQoL) that have been reported in systematic ...
Josep-Maria Losilla   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A new application of contextualist methodology in case research

open access: yes, 2006
Contextualist methodology is the main focus of discussion in this paper, and its attributes as a rigorous approach to case study methodology are discussed. In a departure from the usual practice of applying this methodology to processes of organisational
Chapman, Judith A.
core  

Computational Communication Science| Computational Communication Science: A Methodological Catalyzer for a Maturing Discipline

open access: yesInternational Journal of Communication, 2019
This article reviews the opportunities and challenges for computational research methods in the field of communication. Among the social sciences, communication stands out as a discipline with a relatively low-profile institutionalized focus on the in ...
Martin Hilbert   +15 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

REENGINEERING PROSES BISNIS : TINJAUAN KONSEPTUAL DAN METODOLOGI

open access: yesJurnal Manajemen dan Wirausaha, 1999
Business process reengineering is fundamental rethinking and radical redesign of an organization's business processes that leads the organization to achieve dramatic improvement in business performance.
Lena Ellitan
doaj  

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