Results 91 to 100 of about 9,397,880 (350)

Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model

Drug Design, Development and Therapy
Meimei Chen,1,2,* Kaiyue Huang,1,2,* Wenqian Luo,1,2 Fei Zhang,1,2 Huijuan Gan,1,2 Zhaoyang Yang1– 3 1College of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, People’s Republic of
Chen M, Huang K, Luo W, Zhang F, Gan H, Yang Z   +5 more
doaj  

The impact of coffee on human health

Journal of Education, Health and Sport, 2019
Introduction: Coffee is one of the most popular beverages in the world. It contains lots of biologically active ingredients. These compounds not only have aromatic properties, but many of them also have antioxidant, hepatoprotective, anti-inflammatory ...
Aleksandra Chałupnik, Aleksandra Borkowska, Anna Sobstyl, Zuzanna Chilimoniuk, Maciej Dobosz, Paulina Sobolewska, Halina Piecewicz-Szczęsna   +6 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Range of Body Mass Index and the risk of breast cancer

Journal of Education, Health and Sport, 2018
Introduction. Obesity leads to an increased incidence of many diseases. The research subject of scientists is the impact of obesity on breast cancer as one of the most commonly diagnosed cancers among women. Aim of the study.
Alicja Sobek, Karol Lorenc, Urszula Fałkowska, Julita Poleszak, Halina Piecewicz-Szczęsna   +4 more
doaj   +3 more sources

Barriers to Early Breast Cancer Diagnosis in Sudanese Women Before the War

Breast Cancer: Targets and Therapy
Hana Eltayeb Salih Elamin,1 Hind Eltayeb Salih Elamin,2 Ghada Omer Hamad Abd El-Raheem,3 Mounkaila Noma1 1High Diploma in Research Methodology and Biostatistics, University of Medical Sciences and Technology UMST, Khartoum City, Khartoum State, Sudan ...
Elamin HES, Elamin HES, Abd El-Raheem GOH, Noma M   +3 more
doaj  

How large are the consequences of covariate imbalance in cluster randomized trials: a simulation study with a continuous outcome and a binary covariate at the cluster level

BMC Medical Research Methodology, 2016
Background The number of clusters in a cluster randomized trial is often low. It is therefore likely random assignment of clusters to treatment conditions results in covariate imbalance.
Mirjam Moerbeek, Sander van Schie
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Stress among medical students in Poland

Journal of Education, Health and Sport, 2018
There is no doubt that stress is bonded with daily routine of students. Medical colleges are one of these environments, which are associated with negative impact of stress on many fields of life like physical health, academic feedback and physiological ...
Klaudia Brożyna, Agnieszka Radzka, Jędrzej Tkaczyk, Krystian Ciechański, Halina Piecewicz-Szczęsna   +4 more
doaj   +1 more source

Methodology for quantum logic gate constructions

, 2000
We present a general method to construct fault-tolerant quantum logic gates with a simple primitive, which is an analog of quantum teleportation. The technique extends previous results based on traditional quantum teleportation (Gottesman and Chuang ...
A. Kitaev, A. M. Steane, A. R. Calderbank, A. Steane, C. H. Bennett, D. Gottesman, D. Gottesman, D. Gottesman, Debbie W. Leung, E. Knill, G. Brassard, Isaac L. Chuang, J. L. Hennessey, J. Preskill, M. A. Nielsen, P. O. Boykin, P. Shor, P. Shor, R. Cleve, Xinlan Zhou   +19 more
core   +1 more source