Results 141 to 150 of about 13,399,169 (391)
Youth Internet Safety Study (YISS): Methodology Report. [PDF]
, 2011 The Youth Internet Safety Surveys (YISS‐1, YISS‐2, and YISS‐3) were conducted in order to quantify and detail youth experiences with unwanted or problematic Internet experiences including sexual solicitations, harassment, and unwanted exposure to ...
Jones, Lisa M., Mitchell, Kimberly J
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Web crawler research methodology [PDF]
In economic and social sciences it is crucial to test theoretical models against reliable and big enough databases. The general research challenge is to build up a well-structured database that suits well to the given research question and that is cost ...
Nemeslaki, András +1 more
core
Methodology and Applications of Christian Leadership Ethics [PDF]
, 2018 A fundamental methodology for Christian leadership ethics will be proposed, which has long been pending in the discourse on ethical leadership. It is necessary to first clarify what characterizes leadership ethics, and secondly, what Christian leadership
Kreuer, Ellen, Nass, Elmar
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Pregnancy Risk Assessment Monitoring System (PRAMS): Overview of Design and Methodology
, 2018 Holly B. Shulman +4 more
openalex +2 more sources
Methodology for Water Monitoring in the Upper Troposphere with Raman Lidar at the Haute-Provence Observatory [PDF]
, 2009 Christophe Hoareau +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source