Results 151 to 160 of about 9,808,147 (301)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Correction: Multi-trait and multi-environment genomic prediction enhances yield components improvement in durum wheat. [PDF]

Front Plant Sci
Puglisi D, Crossa J, Cuevas J, Fania F, Afshari-Behbahanizadeh S, Vitale P, De Vita P.   +6 more
europepmc   +1 more source

Jurimetrics: The Methodology of Legal Inquiry [PDF]

, 1963
Loevinger, Lee
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Management of gastric cancer peritoneal metastasis: International Gastric Cancer Association GCPM Working Group consensus statements. [PDF]

Br J Surg
Boshier PR, Chia DKA, Thrumurthy SG, Teh JL, Wobith M, Bencivenga M, Filippini F, Dumitra TC, Burch M, Kim HI, Kobitzsch B, Kodach LL, Quik JSE, Long VD, de Neijs MJ, van der Sluis PC, Leon-Takahashi AM, Woo Y, Chevallay M, Framarini M, Morgagni P, Frejlich E, Grabsch HI, Markar SR, Marrelli D, Park DJ, Sundar R, Xu Z, Linn KK, Yang HK, Kitayama J, Zhu Z, Rha SY, Wijnhoven B, Yamashita H, Yong WP, de la Fouchardière C, Nilsson M, Ishigami H, Van Sandick JW, Lordick F, Badgwell BD, So JBY.   +42 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

International neuroblastoma risk group consortium: a model of networking for rare cancers. [PDF]

J Natl Cancer Inst
Cohn SL, London WB, Schleiermacher G, Moreno L, Ambros IM, Ambros PF, Bagatell R, Popovic MB, Beiske KH, Berthold F, Birz S, Brisse HJ, Brodeur GM, Brock PR, Burchill S, Eggert A, Federico SM, Fischer M, Furner BT, Hero B, Machin D, Kamijo T, Matthay KK, Nakagawara A, Naranjo A, Pötschger U, Valteau-Couanet D, Watkins MT, Irwin MS, Volchenboum SL, Park JR, Pearson ADJ.   +31 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Commentary Paper on Cooling Flavors in Cigarette and Non-Cigarette Tobacco Products. [PDF]

Nicotine Tob Res
Bansal-Travers M, Villanti AC, Page MK, Goniewicz ML, O'Connor RJ, Giovenco DP, Krishnan-Sarin S, Bold KW, Barnes AJ, Price SM.   +9 more
europepmc   +1 more source