Results 161 to 170 of about 9,808,147 (301)

‘Problematic methodology’ [PDF]

Spinal Cord Series and Cases, 2017
Michael D, Stillman, Steve, Williams, Daniel, Graves   +2 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Evaluating Australia's "MyMedicare" voluntary patient registration system: the prospective evaluation of patient registration study protocol. [PDF]

Front Health Serv
Harrison R, Chauhan A, Mitchell R, Raichland S, Arnolda G, Braithwaite J, Westbrook JI, Manias E, Mahadeva J, Newman B, Walsan R, Churruca K, Ricketts S, Spencer R, Sarwar M, Liang J, Pallavicini D, Baumgartner DD, Bowen K, Gillies D, Badr C, Kangru K, Chua AV, Hardy L, Judd-Lamm S, Moore K, Edwards L, Vagholkar S.   +27 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Definition of the terms used to describe psoriatic disease datasets: a HIPPOCRATES initiative. [PDF]

Ther Adv Musculoskelet Dis
FitzGerald O, Smith C, Huppertz C, Brom M, Bruno D, Helliwell PS, van de Sande M, de Wit M, Werner L, Ioannidis V, Marek D, Ibberson M, Pennington SR, Koehm M, Behrens F.   +14 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Research methodology

, 2022
openaire   +3 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Correction: Computational discovery of SARS-CoV-2 viral entry inhibitory peptides from <i>Androctonus mauretanicus</i> scorpion venom: molecular docking and molecular dynamics simulations targeting the spike protein. [PDF]

Front Bioinform
Chahir R, Redouane S, Galan J, Hboub H, Aserrar L, Chakir S, Lahlou AS, Aassila H, El Fatimy R, Oukkache N.   +9 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source