Results 141 to 150 of about 2,951,798 (263)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Developing Public-Friendly Visualisations to Improve PPIE Glossaries for Statistical Methodology Research. [PDF]

Health Expect
Nevill CR, Cooper H, Czyznikowska B, Fairgrieve L, Greenwood J, Grewal-Santini G, Nevill J, Teece L, Wells M, Freeman SC, Booth S.   +10 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Disease Burden of Type 2 Diabetes Among Young Adults in Asia: An Analysis From the Global Burden of Disease Study 2021

Journal of Diabetes Research
Ruoting Wang, Gregory Y. H. Lip, Yingxin Liu, Ningyu Qi, Xuerui Bai, Lehana Thabane, Guowei Li, Harriette G. C. Van Spall   +7 more
doaj   +1 more source

A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology. [PDF]

Synth Biol (Oxf)
Bull T, Carlsen L, Hoglund N, Blarr J, Ciernia M, Daughtrey H, Gulnac K, Kathan Z, Labovitz B, Lonergan R, McDermott M, Medina A, Mikol Z, Miller Z, Prahl K, Rifai C, Schrems E, Shinkawa F, Summerfield J, Thevarajah E, Wagner S, Zimmerman T, Khakhar A.   +22 more
europepmc   +1 more source

Research methodology

, 2022
openaire   +2 more sources

The Methodology of Morality – the Morality of Methodology [PDF]

Rocznik Teologii Katolickiej, 2007
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Correction to "The Role of Dopamine Signaling and Neuroinflammation in Age-Related Cognitive Dysfunction". [PDF]

Brain Behav
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source