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Methodologies in practice based projects as used by work based learning students in the former School of health, biological and environmental sciences [PDF]

, 2003
Learning through work has long been a central tenet in the training and education of health care professionals, particularly nurses, and so transference of the principles of Work Based Learning (WBL) to the Health Campus has built effectively on previous structures.
Barbara Workman
openaire   +2 more sources

Team-Based Learning and Threshold Concepts in Biological Security and Dual-Use: Toward a Transformative Biological Security Pedagogy—The Game Changing Implications of CRISPR/Cas and the Design of a Novel Methodology for Influencing the Culture of Life and Associated Science through Awareness Raising and Education

Creative Education
Yes CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technologies appear to be a game-changer and suggest great potential for genome manipulation and for developments in next-generation therapeutics. Ethical, legal and social concerns have been raised in light of recent applications in humans.
Whitby, Simon, Dando, Malcolm, McCarter, Rebecca, Tweddell, Simon   +3 more
  +5 more sources

Review: Radiotracer Methodology in Biological Science, by C. H. Wang and David L. Willis

The American Biology Teacher, 1966
G. E. Stone
openaire   +2 more sources

Radiotracer methodology in the biological, environmental and physical sciences (Wang, C. H.; Willis, D. L.; Loveland, W. D.) [PDF]

Journal of Chemical Education, 1976
L. B. Church
openaire   +2 more sources

Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

iScience, 2021
Summary: Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of the
Niklas Handin, Evgeniya Mickols, Magnus Ölander, Jakob Rudfeldt, Kristin Blom, Frida Nyberg, Wojciech Senkowski, Jozef Urdzik, Varun Maturi, Mårten Fryknäs, Per Artursson   +10 more
doaj   +1 more source

Top-down reconfiguration of SMA cortical connectivity during action preparation

iScience, 2023
Summary: The Bereitschaftspotential (BP), a scalp potential recorded in humans during action preparation, is characterized by a slow amplitude increase over fronto-central regions as action execution approaches.
Valentina Bianco, Eleonora Arrigoni, Francesco Di Russo, Leonor Josefina Romero Lauro, Alberto Pisoni   +4 more
doaj   +1 more source

Influence of data sampling methods on the representation of neural spiking activity in vivo

iScience, 2022
Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden, Amanda M. Brown, Roy V. Sillitoe   +2 more
doaj   +1 more source

Optimization of the 16S rRNA sequencing analysis pipeline for studying in vitro communities of gut commensals

iScience, 2022
Summary: While microbial communities inhabit a wide variety of complex natural environments, in vitro culturing enables highly controlled conditions and high-throughput interrogation for generating mechanistic insights.
Arianna I. Celis, Andrés Aranda-Díaz, Rebecca Culver, Katherine Xue, David Relman, Handuo Shi, Kerwyn Casey Huang   +6 more
doaj   +1 more source

Visualizing lymphocytic choriomeningitis virus infection in cells and living mice

iScience, 2022
Summary: Mammarenavirus are a large family of enveloped negative-strand RNA viruses that include several agents responsible for severe hemorrhagic fevers.
Yuxi Wen, Huan Xu, Weiwei Wan, Weijuan Shang, Runming Jin, Fen Zhou, Heng Mei, Jingshi Wang, Gengfu Xiao, Hongbo Chen, Xiaoyan Wu, Leike Zhang   +11 more
doaj   +1 more source

Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus

iScience, 2023
Summary: A simple and robust cell culture system is essential for generating authentic SARS-CoV-2 stocks for evaluation of viral pathogenicity, screening of antiviral compounds, and preparation of inactivated vaccines.
Da-Yuan Chen, Jacquelyn Turcinovic, Shuchen Feng, Devin J. Kenney, Chue Vin Chin, Manish C. Choudhary, Hasahn L. Conway, Marc Semaan, Brianna J. Close, Alexander H. Tavares, Scott Seitz, Nazimuddin Khan, Sebastian Kapell, Nicholas A. Crossland, Jonathan Z. Li, Florian Douam, Susan C. Baker, John H. Connor, Mohsan Saeed   +18 more
doaj   +1 more source