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Methodological studies of PIXE on biological and environmental science [PDF]
The Van de Graaff Facility at IHEP is mainly used for PIXE research work especially on biologicial and environmental science. The sensitivities and the number of analyzed trace elements were improved greatly using special absorbers for bone and whole blood samples. Quite good results were obtained for different biomedical research work. Several methods
Sha Yin+9 more
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Yes CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technologies appear to be a game-changer and suggest great potential for genome manipulation and for developments in next-generation therapeutics. Ethical, legal and social concerns have been raised in light of recent applications in humans.
Simon M. Whitby+3 more
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Methodologies in practice based projects as used by work based learning students in the former School of health, biological and environmental sciences [PDF]
Learning through work has long been a central tenet in the training and education of health care professionals, particularly nurses, and so transference of the principles of Work Based Learning (WBL) to the Health Campus has built effectively on previous structures.
Barbara Workman
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Radiotracer methodology in the biological, environmental and physical sciences (Wang, C. H.; Willis, D. L.; Loveland, W. D.) [PDF]
L. B. Church
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This review surveys the emergence of electron probe X-ray microanalysis as a quantitative method for measuring the chemical elements in situ. The extension of the method to the biological sciences under the influence of Ted Hall is reviewed. Some classical experiments by Hall and his colleagues in Cambridge, UK, previously unpublished, are described ...
Brij L. Gupta
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Review: Radiotracer Methodology in Biological Science, by C. H. Wang and David L. Willis
G. E. Stone
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Algebraic Model Selection and Experimental Design in Biological Data Science [PDF]
Design of experiments and model selection, though essential steps in data science, are usually viewed as unrelated processes in the study and analysis of biological networks. Not accounting for their inter-relatedness has the potential to introduce bias and increase the risk of missing salient features in the modeling process.
arxiv +1 more source
Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
Summary: Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of the
Niklas Handin+10 more
doaj
A Model of the Cellular Iron Homeostasis Network Using Semi-Formal Methods for Parameter Space Exploration [PDF]
This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to biological systems is to get access to the relevant parameter sets despite gaps in the available knowledge.
arxiv +1 more source