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Methodological studies of PIXE on biological and environmental science [PDF]

open access: greenNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1996
The Van de Graaff Facility at IHEP is mainly used for PIXE research work especially on biologicial and environmental science. The sensitivities and the number of analyzed trace elements were improved greatly using special absorbers for bone and whole blood samples. Quite good results were obtained for different biomedical research work. Several methods
Sha Yin   +9 more
openalex   +3 more sources

Team-Based Learning and Threshold Concepts in Biological Security and Dual-Use: Toward a Transformative Biological Security Pedagogy —The Game Changing Implications of CRISPR/Cas and the Design of a Novel Methodology for Influencing the Culture of Life and Associated Science through Awareness Raising and Education

open access: bronzeCreative Education
Yes CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technologies appear to be a game-changer and suggest great potential for genome manipulation and for developments in next-generation therapeutics. Ethical, legal and social concerns have been raised in light of recent applications in humans.
Simon M. Whitby   +3 more
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Methodologies in practice based projects as used by work based learning students in the former School of health, biological and environmental sciences [PDF]

open access: closed, 2003
Learning through work has long been a central tenet in the training and education of health care professionals, particularly nurses, and so transference of the principles of Work Based Learning (WBL) to the Health Campus has built effectively on previous structures.
Barbara Workman
openalex   +1 more source

Ted Hall and the science of biological microprobe X-ray analysis: a historical perspective of methodology and biological dividends.

open access: closedScanning microscopy, 1991
This review surveys the emergence of electron probe X-ray microanalysis as a quantitative method for measuring the chemical elements in situ. The extension of the method to the biological sciences under the influence of Ted Hall is reviewed. Some classical experiments by Hall and his colleagues in Cambridge, UK, previously unpublished, are described ...
Brij L. Gupta
openalex   +3 more sources

Algebraic Model Selection and Experimental Design in Biological Data Science [PDF]

open access: yesAdvances in Applied Mathematics, 133 (2022), 2021
Design of experiments and model selection, though essential steps in data science, are usually viewed as unrelated processes in the study and analysis of biological networks. Not accounting for their inter-relatedness has the potential to introduce bias and increase the risk of missing salient features in the modeling process.
arxiv   +1 more source

Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

open access: yesiScience, 2021
Summary: Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of the
Niklas Handin   +10 more
doaj  

A Model of the Cellular Iron Homeostasis Network Using Semi-Formal Methods for Parameter Space Exploration [PDF]

open access: yesEPTCS 92, 2012, pp. 42-57, 2012
This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to biological systems is to get access to the relevant parameter sets despite gaps in the available knowledge.
arxiv   +1 more source

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