Results 131 to 140 of about 3,716,507 (339)

Aligning Statistical Dynamics Captures Biological Network Functioning [PDF]

open access: yesarXiv, 2019
Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities spanning the physical, biological, and social.
arxiv  

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1117-1131, April 2025.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto   +3 more
wiley   +1 more source

Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection

open access: yesiScience
Summary: Monitoring in vivo viral dynamics can improve our understanding of pathogenicity and tissue tropism. Because the gene size of RNA viruses is typically small, NanoLuc is the primary choice for accommodation within viral genome.
Tomokazu Tamura   +17 more
doaj  

NEW METHODOLOGICAL METHODS OF TEACHING BIOLOGICAL SCIENCE

open access: yes
In the course of this research, the features of teaching biology using modern methods were analyzed. The methodology of teaching biology as a pedagogical science is inextricably linked with didactics. Based on the unique characteristics of school biology, the methodology of teaching biology develops theoretical and practical problems of the content ...
openaire   +2 more sources

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Revealed comparative advantages in scientific and technological disciplines in Uruguay [PDF]

open access: yes
Based on bibliometric information from Scopus for the period 1996-2019, this document characterizes the evolution of Uruguayan scientific production and establishes the areas in which the country has a revealed comparative advantage (RCA). Methodologically, it is proposed that there is a RCA in an area if this area has a greater share in national ...
arxiv   +1 more source

Economics, Biology, and Culture: Hodgson on History [PDF]

open access: yes, 2003
This book addresses what the author claims, with considerable justification, to be the foremost challenge confronting the social and behavioral sciences today: the problem of historical specificity.
Field, Alexander J.
core   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits   +7 more
wiley   +1 more source

Complexity, Disorder, and Functionality of Nanoscale Materials [PDF]

open access: yesarXiv
Nature hosts a wealth of materials showcasing intricate structures intertwining order, disorder, and hierarchy, delivering resilient multifunctionality surpassing perfect crystals or simplistic disordered materials. The engineering of such materials through nanoparticle assembly represents a burgeoning field, poised with potential to yield sustainable ...
arxiv  

Whence philosophy of biology? [PDF]

open access: yes, 2006
A consensus exists among contemporary philosophers of biology about the history of their field. According to the received view, mainstream philosophy of science in the 1930s, 40s, and 50s focused on physics and general epistemology, neglecting analyses ...
Byron (formerly Baker), Jason M.
core   +1 more source

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