Results 201 to 210 of about 119,724,969 (305)

Clinical Significance of a Cell-Of-Origin-Based Classification in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Sci
Kikuchi T, Ako S, Kato H, Kinugasa H, Uchida M, Oda T, Hirai R, Matsumi A, Miyamoto K, Terasawa H, Fujii Y, Uchida D, Matsumoto K, Tsutsumi K, Horiguchi S, Yasui K, Fuji T, Takagi K, Kato H, Honda T, Otsuka F, Otsuka M.   +21 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Chemoselective halogenation of premarineosin A for next-generation antimalarial development.

Org Biomol Chem
Harris NR, Amin S, Curtis BJ, Teklemichael AA, Dranchak P, McBride CM, Verhey-Henke L, Warrell CJ, Dulaney WM, Oliphant EN, Inglese J, Su XZ, Sherman DH, Pereira F.   +13 more
europepmc   +1 more source

Correction: Supplementation of <i>Saussurea costus</i> root alleviates sodium nitrite-induced hepatorenal toxicity by modulating metabolic profile, inflammation, and apoptosis. [PDF]

Front Pharmacol
Elshaer SE, Hamad GM, Sobhy SE, Darwish AMG, Baghdadi HH, Abo Nahas HH, El-Demerdash FM, Kabeil SSA, Altamimi AS, Al-Olayan E, Alsunbul M, Docmac OK, Jaremko M, Hafez EE, Saied EM.   +14 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Modtector: ultra-fast modification signal mining on mapped sequencing reads. [PDF]

Bioinformatics
Zhou T, Hong Y, Li P, Liu X, Zhang J, Wang X, Li A, Sun L.   +7 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

From Data to Discovery: Characterizing the Scope and Limitations of Seedling Trait Studies in the U.S. With the EPiC Database. [PDF]

Ecol Evol
Johnson NM, Lenzo LJ, Renner AG, Al-Shayeb SMA, Larson JE, Garbowski M, Slate ML, Alison AC, Barga SC, Carlisle TC, Currens A, Dorrell M, Havrilla CA, LaForgia ML, Paradis A, Newman MM, Rosa S, Sershen M, Winkler DE, Wood H, Foxx AJ.   +20 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Clinical evaluation of early implant stability using resonance frequency analysis: a multicenter observational study. [PDF]

Front Dent Med
Rodrigues SJ, Shenoy VK, Upadhya MK, Kulkarni MR, Kumar ABT, Ponnanna AA, Mamatha NS.   +6 more
europepmc   +1 more source