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The therapeutic applications of mesenchymal stromal cells from human perinatal tissues in autoimmune diseases

open access: yesStem Cell Research & Therapy, 2021
The autoimmune diseases are characterized by overactivation of immune cells, chronic inflammation, and immune response to self-antigens, leading to the damage and dysfunction of multiple organs.
Chao Yang   +5 more
doaj   +1 more source

Mesenchymal stem cells isolated from human periodontal ligament [PDF]

open access: yesArchives of Biological Sciences, 2014
Mesenchymal stem cells (MSCs) were isolated from human periodontal ligament (hPDL-MSCs) and characterized by their morphology, clonogenic efficiency, proliferation and differentiation capabilities.
Miletić Maja   +7 more
doaj   +1 more source

Inter-organellar and systemic responses to impaired mitochondrial matrix protein import in skeletal muscle

open access: yesCommunications Biology, 2022
Muscular pathologies, including muscular dystrophy, are caused by a number of cellular and metabolic perturbations; here, consequences of GRPEL1-null disrupted mitochondrial matrix protein import on muscle atrophy, metabolism, and stress responses are ...
Nirajan Neupane   +8 more
doaj   +1 more source

Mouse Degenerating Optic Axons Survived by Human Embryonic Stem Cell-Derived Neural Progenitor Cells [PDF]

open access: yesCell Journal, 2022
Objective: Any damage to the optic nerve can potentially lead to degeneration of non-regenerating axons and ultimately death of retinal ganglion cells (RGCs) that in most cases, are not curable by surgery or medication.
Shiva Nemati   +7 more
doaj   +1 more source

In vivo performance of Al2O3-Ti bone implants in the rat femur

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Alumina-titanium (Al2O3-Ti) biocomposites have been recently developed with improved mechanical properties for use in heavily loaded orthopedic sites. Their biological performance, however, has not been investigated yet. Methods The aim of the
Marjan Bahraminasab   +5 more
doaj   +1 more source

Therapy resistance on the RADar in ovarian cancer

open access: yesEMBO Molecular Medicine, 2021
Ovarian cancer has the worst prognosis of all gynecological cancers with high‐grade serous ovarian cancer (HGSOC) accounting for the majority of ovarian cancer deaths.
Jonas Schwickert   +2 more
doaj   +1 more source

Effects of Co-Administration of Bone Marrow Stromal Cells and L-Carnitine on The Recovery of Damaged Ovaries by Performing Chemotherapy Model in Rat [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2019
Background L-carnitine (Lc) as a type of flavonoid antioxidants and bone marrow stromal cells (BMSCs) as a type of mesenchymal stem cells may recover damaged ovaries.
Sam Zarbakhsh   +6 more
doaj   +1 more source

A Comparative Study of Cell Culture Conditions during Conversion from Primed to Naive Human Pluripotent Stem Cells

open access: yesBiomedicines, 2022
The successful reprogramming of human somatic cells into induced pluripotent stem cells (hiPSCs) represented a turning point in the stem cell research field, owing to their ability to differentiate into any cell type with fewer ethical issues than human ...
Irene Romayor   +8 more
doaj   +1 more source

Topical Umbilical Cord Serum for Corneal Epithelial Defects after Diabetic Vitrectomy

open access: yesJournal of Ophthalmic & Vision Research, 2020
Purpose: To evaluate the role of topical umbilical cord serum (TUCS) therapy in treating corneal epithelial defects (CEDs) after diabetic vitrectomy. Methods: In this double-masked, randomized clinical trial, we included 80 eyes of 80 patients who ...
Siamak Moradian   +4 more
doaj   +1 more source

MicroRNAs as Important Regulators Mediate the Multiple Differentiation of Mesenchymal Stromal Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
MicroRNAs (miRNAs) are endogenous short non-encoding RNAs which play a critical role on the output of the proteins, and influence multiple biological characteristics of the cells and physiological processes in the body.
Chao Yang   +5 more
doaj   +1 more source

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