Results 11 to 20 of about 1,695,865 (287)
Biomedicines, 2022 The successful reprogramming of human somatic cells into induced pluripotent stem cells (hiPSCs) represented a turning point in the stem cell research field, owing to their ability to differentiate into any cell type with fewer ethical issues than human ...
Irene Romayor +8 more
doaj +1 more source
Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy [PDF]
, 2018 Unintended outcomes of cancer therapy include ionizing radiation (IR)-induced stem cell depletion, diminished regenerative capacity, and accelerated aging.
Fabbrizi, Maria Rita +6 more
core +3 more sources
MicroRNAs as Important Regulators Mediate the Multiple Differentiation of Mesenchymal Stromal Cells
Frontiers in Cell and Developmental Biology, 2021 MicroRNAs (miRNAs) are endogenous short non-encoding RNAs which play a critical role on the output of the proteins, and influence multiple biological characteristics of the cells and physiological processes in the body.
Chao Yang +5 more
doaj +1 more source
, 2008 Nowadays, stem cell represents one of the most promising research areas in regenerative medicine. They are defined by two basic properties: the ability to proliferate by a process of self-renewal and the potential to differentiate into specialized cell types.
Poo, ME, Simon, C
+6 more sources
Topical Umbilical Cord Serum for Corneal Epithelial Defects after Diabetic Vitrectomy
Journal of Ophthalmic & Vision Research, 2020 Purpose: To evaluate the role of topical umbilical cord serum (TUCS) therapy in treating corneal epithelial defects (CEDs) after diabetic vitrectomy. Methods: In this double-masked, randomized clinical trial, we included 80 eyes of 80 patients who ...
Siamak Moradian +4 more
doaj +1 more source
Scientific Reports, 2022 Extracellular vesicles (EVs) have therapeutic effects on osteoarthritis (OA). Some recent strategies could elevate EV's therapeutic properties including cell aggregation, co-culture, and 3D culture.
Abazar Esmaeili +5 more
doaj +1 more source
Differentiating functional human islet-like aggregates from pluripotent stem cells
STAR Protocols, 2022 Summary: We present here a robust and reliable protocol by which to differentiate pancreatic islet-like aggregates (SC-islets) from human pluripotent stem cells.
Tom Barsby +8 more
doaj +1 more source
Biomolecules, 2023 Periodontitis (PD) is a degenerative, bacteria-induced chronic disease of periodontium causing bone resorption and teeth loss. It includes a strong reaction of immune cells through the secretion of proinflammatory factors such as Interleukin-17 (IL-17 ...
Ivana Okić Đorđević +8 more
doaj +1 more source
Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]
, 2018 Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey +2 more
core +2 more sources
Interleukin-17 modulates uPA and MMP2 expression in human periodontal ligament mesenchymal stem cells: Involvement of the ERK1/2 MAPK pathway [PDF]
Archives of Biological Sciences, 2022 Periodontal disease is a chronic infection of periodontal tissue characterized by extracellular matrix (ECM) degradation due to increased expression of plasminogen activators and matrix metalloproteinases (MMPs) and various proinflammatory cytokines ...
Okić-Đorđević Ivana +8 more
doaj +1 more source