Results 41 to 50 of about 2,855,746 (355)

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D, Suzuki, H., Forrest, Alistair R. R., Hasegawa, Y., Suzuki, H, Ovchinnikov, Dmitry A., Hitchens, Kelly J., Takahashi, N., Forrest, A.R.R., Kenna, Tony, Suzuki, Harukazu, Tang, D., Joshi, Anagha, Hayashizaki, Y., Wolvetang, Ernst, Tang, Dave, Suzuki, H., Forrest, Alistair R R, FANTOM Consortium, the FANTOM consortium, Vijayan, Dipti, Wells, Christine A., Hasegawa, Y, Hayashizaki, Yoshihide, Forrest, ARR, Takahashi, Naoko, Briggs, James, Hasegawa, Yuki, Blumenthal, Antje, Tang, D., Hayashizaki, Y, ?, ?, Sajantila, Antti, Hasegawa, Y., Takahashi, N, Takahashi, N., Forrest, A. R., Beckhouse, Anthony G., FANTOM Consortium,, Hayashizaki, Y.   +39 more
core   +1 more source

Mesenchymal stem cells-derived exosomes for drug delivery

Stem cell research & therapeutics, 2021
Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid bilayers without organelles. In recent years, an increasing number of researchers have focused on the use of exosomes for drug delivery. Targeted drug delivery in the
Yao Sun, Guoliang Liu, Kai Zhang, Qian Cao, Tongjun Liu, Jiannan Li   +5 more
semanticscholar   +1 more source

Co-aggregation of MSC/chondrocyte in a dynamic 3D culture elevates the therapeutic effect of secreted extracellular vesicles on osteoarthritis in a rat model

Scientific Reports, 2022
Extracellular vesicles (EVs) have therapeutic effects on osteoarthritis (OA). Some recent strategies could elevate EV's therapeutic properties including cell aggregation, co-culture, and 3D culture.
Abazar Esmaeili, Samaneh Hosseini, Amir Kamali, Maryam Hosseinzadeh, Faezeh Shekari, Mohamadreza Baghaban Eslaminejad   +5 more
doaj   +1 more source

Differentiating functional human islet-like aggregates from pluripotent stem cells

STAR Protocols, 2022
Summary: We present here a robust and reliable protocol by which to differentiate pancreatic islet-like aggregates (SC-islets) from human pluripotent stem cells.
Tom Barsby, Hazem Ibrahim, Väinö Lithovius, Hossam Montaser, Diego Balboa, Eliisa Vähäkangas, Vikash Chandra, Jonna Saarimäki-Vire, Timo Otonkoski   +8 more
doaj   +1 more source

Stem Cell For Researchers

, 2022
1.introduction 2. Properties Self-renewal Potency meaning Identification 3. Embryonic stem cells 4. Amniotic 5. Fetal stem cells 6. Adult stem cells 7. Dental stem and drugs 8. Cancer stem cell and drugs 9. Induced pluripotent stem cells 10.
Aliasghar Tabatabaei mohammadi, Narjes sadat Farizani gohari, Seyyed Ghavam Shafagh, Hossein Bagheri, Houra Fazlavargharebagh, Maryam Yousefi dehbidi, Ali Jahani heydarlou, Yoones Sadabadi, Mohammad hadi Hosnaei, Sevda Hasanzade, Fatemeh Asghariyan devin, Fatemeh Aghaei, Erfan Ghanbarzadeh   +12 more
  +6 more sources

Generation and characterization of erythroid cells from human embryonic stem cells and induced pluripotent stem cells : an overview [PDF]

, 2011
Because of the imbalance in the supply and demand of red blood cells (RBCs), especially for alloimmunized patients or patients with rare blood phenotypes, extensive research has been done to generate therapeutic quantities of mature RBCs from ...
Bönig, Halvard-Björn, Chang, Kai-Hsin, Kai-Hsin Chang, Thalia Papayannopoulou, Halvard Bonig, Papayannopoulou, Thalia   +5 more
core   +1 more source

Human mesenchymal stem cells

Cell Proliferation, 2021
Mesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self‐renewal capacity, multipotency and potent immunomodulatory effects on immune cells.
Xiaoyong Chen, Jing Huang, Jun Wu, Jie Hao, Bo‐qiang Fu, Ying Wang, B. Zhou, Tao Na, Jun Wei, Yong Zhang, Qiyuan Li, Shijun Hu, Jiaxi Zhou, Junying Yu, Zhaohui Wu, Huanxin Zhu, Jiani Cao, Lei Wang, Yaojin Peng, Lingmin Liang, Aijin Ma, Yu Zhang, T. Zhao, A. Xiang   +23 more
semanticscholar   +1 more source

The Role of Doxycycline and IL-17 in Regenerative Potential of Periodontal Ligament Stem Cells: Implications in Periodontitis

Biomolecules, 2023
Periodontitis (PD) is a degenerative, bacteria-induced chronic disease of periodontium causing bone resorption and teeth loss. It includes a strong reaction of immune cells through the secretion of proinflammatory factors such as Interleukin-17 (IL-17 ...
Ivana Okić Đorđević, Tamara Kukolj, Milena Živanović, Sanja Momčilović, Hristina Obradović, Anđelija Petrović, Slavko Mojsilović, Drenka Trivanović, Aleksandra Jauković   +8 more
doaj   +1 more source

Stem Cell Research in Singapore [PDF]

Cell, 2008
Singapore is investing heavily in stem cell research. This investment is part of an ambitious biomedical science initiative designed to enhance its thriving economy.
openaire   +2 more sources

Interleukin-17 modulates uPA and MMP2 expression in human periodontal ligament mesenchymal stem cells: Involvement of the ERK1/2 MAPK pathway [PDF]

Archives of Biological Sciences, 2022
Periodontal disease is a chronic infection of periodontal tissue characterized by extracellular matrix (ECM) degradation due to increased expression of plasminogen activators and matrix metalloproteinases (MMPs) and various proinflammatory cytokines ...
Okić-Đorđević Ivana, Kukolj Tamara, Obradović Hristina, Trivanović Drenka, Petrović Anđelija, Mojsilović Slavko, Miletić Maja, Bugarski Diana, Jauković Aleksandra   +8 more
doaj   +1 more source